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SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu16155 NM_001042496 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 5, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu16186 NM_001042495 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu16248 NM_001042497 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 6, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu16186 NM_001042494 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu18029 NM_133647 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu18033 NM_005135 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu48703 XM_006720793 PREDICTED: Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu16155C NM_001042496 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 5, mRNA. Customized vector On-demand 25 $1699.00
OHu16186C NM_001042495 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 4, mRNA. Customized vector On-demand 25 $1699.00
OHu16248C NM_001042497 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 6, mRNA. Customized vector On-demand 25 $1699.00
OHu16186C NM_001042494 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 3, mRNA. Customized vector On-demand 25 $1699.00
OHu18029C NM_133647 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 1, mRNA. Customized vector On-demand 25 $1699.00
OHu18033C NM_005135 Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant 2, mRNA. Customized vector On-demand 25 $1699.00
OHu48703C XM_006720793 PREDICTED: Homo sapiens solute carrier family 12 (potassium/chloride transporter), member 6 (SLC12A6), transcript variant X1, mRNA. Customized vector On-demand 25 $1699.00

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Gene Symbol SLC12A6
Entrez Gene ID 9990
Full Name solute carrier family 12 (potassium/chloride transporter), member 6
Synonyms ACCPN, KCC3, KCC3A, KCC3B
General protein information
Preferred Names
solute carrier family 12 member 6
Names
solute carrier family 12 member 6
K-Cl cotransporter 3
potassium-chloride transporter-3a
potassium-chloride transporter-3b
potassium chloride cotransporter 3
potassium chloride cotransporter KCC3a-S3
electroneutral potassium-chloride cotransporter 3
solute carrier family 12 (potassium/chloride transporters), member 6
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q13

Summary This gene is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq, Jul 2008].
Disorder

MIM: 604878

Agenesis of the corpus callosum with peripheral neuropathy, 218000

mRNA Protein Product Sequence Price Select
NM_001042494, 110224451 NP_001035959, 110224452 solute carrier family 12 member 6 isoform c ORF Sequence $1500.00
NM_001042495, 110224453 NP_001035960, 110224454 solute carrier family 12 member 6 isoform c ORF Sequence $1500.00
NM_001042496, 110224455 NP_001035961, 110224456 solute carrier family 12 member 6 isoform d ORF Sequence $1500.00
NM_001042497, 110224457 NP_001035962, 110224458 solute carrier family 12 member 6 isoform e ORF Sequence $1500.00
NM_005135, 110224450 NP_005126, 4826780 solute carrier family 12 member 6 isoform b ORF Sequence $1500.00
NM_133647, 110224448 NP_598408, 110224449 solute carrier family 12 member 6 isoform a ORF Sequence $1500.00
XM_006720793, 578827667 XP_006720856, 578827668 solute carrier family 12 member 6 isoform X1 ORF Sequence $1500.00
Reactome
REACT_19118SLC-mediated transmembrane transport
REACT_19315Cation-coupled Chloride cotransporters
REACT_19397Transport of inorganic cations/anions and amino acids/oligopeptides
REACT_15518Transmembrane transport of small molecules
Homo sapiens (human)SLC12A6NP_598408.1
Pan troglodytes (chimpanzee)SLC12A6XP_001173480.1
Macaca mulatta (Rhesus monkey)SLC12A6XP_002804750.1
Canis lupus familiaris (dog)SLC12A6XP_005638240.1
Bos taurus (cattle)SLC12A6NP_001180045.1
Mus musculus (house mouse)Slc12a6NP_598410.2
Rattus norvegicus (Norway rat)Slc12a6NP_001103100.1
Danio rerio (zebrafish)slc12a7bXP_696060.6
Xenopus (Silurana) tropicalis (western clawed frog)slc12a6NP_001072576.1
Process
IDNameEvidence
GO:0001525angiogenesisNAS
GO:0006811ion transportIDA
GO:0006811ion transportTAS
GO:0006813potassium ion transportIEA
GO:0006821chloride transportIDA
GO:0010107potassium ion importIDA
GO:0035826rubidium ion transportIMP
GO:0055085transmembrane transportTAS
GO:0071476cellular hypotonic responseIMP
GO:0071477cellular hypotonic salinity responseIDA
GO:1902476chloride transmembrane transportIDA
GO:1902476chloride transmembrane transportIEA
Component
IDNameEvidence
GO:0005886plasma membraneTAS
GO:0016021integral component of membraneNAS
GO:0016323basolateral plasma membraneISS
Function
IDNameEvidence
GO:0015079potassium ion transmembrane transporter activityIDA
GO:0015379potassium:chloride symporter activityIDA
GO:0019901protein kinase bindingIPI
GO:0035827rubidium ion transmembrane transporter activityIMP
GeneCards SLC12A6
UniProt Q6NSI7, Q9UHW9
MIM 604878
HGNC 10914
HPRD 09220

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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