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Sequence in raw or FASTA format:

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PIGK phosphatidylinositol glycan anchor biosynthesis, class K [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_005482 Homo sapiens phosphatidylinositol glycan anchor biosynthesis, class K (PIGK), mRNA. ORF Sequence $344.52
Peptide Services
Antibody Services
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Gene Symbol PIGK
Entrez Gene ID 10026
Full Name phosphatidylinositol glycan anchor biosynthesis, class K
Synonyms GPI8, MGC22559
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p31.1

Summary This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008].
Disorder

MIM: 605087

mRNA Protein Product Sequence Price Select
NM_005482, 110224470 NP_005473, 23199983 GPI-anchor transamidase precursor Full Length $1619.10
ORF Sequence $344.52
KEGG
hsa00563Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Reactome
REACT_1853Post-translational modification: synthesis of GPI-anchored proteins
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_1830Attachment of GPI anchor to uPAR
Homo sapiens (human)PIGKNP_005473.1
Pan troglodytes (chimpanzee)PIGKXP_001168438.1
Macaca mulatta (Rhesus monkey)PIGKXP_001102474.1
Canis lupus familiaris (dog)PIGKXP_853775.1
Bos taurus (cattle)PIGKNP_001071348.1
Mus musculus (house mouse)PigkNP_079938.1
Rattus norvegicus (Norway rat)PigkNP_001011953.1
Gallus gallus (chicken)PIGKNP_001026449.1
Danio rerio (zebrafish)pigkNP_001002149.1
Drosophila melanogaster (fruit fly)CG4406NP_569968.2
Caenorhabditis eleganshpo-4NP_502076.2
Arabidopsis thaliana (thale cress)AT1G08750NP_849616.1
GeneCards PIGK
UniProt Q92643
MIM 605087
Ensembl ENSG00000142892
HGNC 8965
HPRD 05474

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
GPI-anchor transamidase
Names
GPI-anchor transamidase
PIG-K
GPI8 homolog
GPI transamidase subunit
phosphatidylinositol glycan, class K
phosphatidylinositol-glycan biosynthesis class K protein
NP_005473.1

Interactant

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