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ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_005691 Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (ABCC9), transcript variant SUR2A, mRNA. ORF Sequence $1627.50
Peptide Services
Antibody Services
Protein Services
NM_020297 Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (ABCC9), transcript variant SUR2B, mRNA. ORF Sequence $1627.50
Peptide Services
Antibody Services
Protein Services


Gene Symbol ABCC9
Entrez Gene ID 10060
Full Name ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Synonyms ABC37, CMD1O, FLJ36852, SUR2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p12.1

Summary The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011].
Disorder

MIM: 601439

Cardiomyopathy, dilated, 1O, 608569 (3)

mRNA Protein Product Sequence Price Select
NM_005691, 110832834 NP_005682, 110832835 ATP-binding cassette sub-family C member 9 isoform SUR2A Full Length $1634.50
ORF Sequence $1627.50
NM_020297, 110832836 NP_064693, 110832837 ATP-binding cassette sub-family C member 9 isoform SUR2B Full Length $0.00
ORF Sequence $1627.50
KEGG
hsa02010ABC transporters
Reactome
REACT_75775ATP sensitive Potassium channels
REACT_75908Potassium Channels
REACT_13685Neuronal System
REACT_15518Transmembrane transport of small molecules
REACT_15480ABC-family proteins mediated transport
REACT_75918Inwardly rectifying K+ channels
Homo sapiens (human)ABCC9NP_064693.2
Pan troglodytes (chimpanzee)ABCC9XP_001149414.1
Macaca mulatta (Rhesus monkey)ABCC9XP_001098888.1
Canis lupus familiaris (dog)ABCC9XP_852746.1
Bos taurus (cattle)ABCC9XP_002687783.1
Mus musculus (house mouse)Abcc9NP_035641.1
Rattus norvegicus (Norway rat)Abcc9NP_037172.2
Gallus gallus (chicken)ABCC9XP_003640452.1
Danio rerio (zebrafish)abcc9NP_001025325.1
GeneCards ABCC9
UniProt O60706
MIM 601439
Ensembl ENSG00000069431
HGNC 60
HPRD 03258

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ATP-binding cassette sub-family C member 9
Names
ATP-binding cassette sub-family C member 9
sulfonylurea receptor 2
ATP-binding cassette transporter sub-family C member 9

Interactant

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