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Sequence in raw or FASTA format:


Blast Method:


PREB prolactin regulatory element binding [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu06465D NM_013388 Homo sapiens prolactin regulatory element binding (PREB), mRNA. pcDNA3.1-C-(k)DYK In-stock 5-7 Starting from $99
OHu35241D XM_006711914 PREDICTED: Homo sapiens prolactin regulatory element binding (PREB), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK On-demand 7-9 Starting from $99
OHu06465C NM_013388 Homo sapiens prolactin regulatory element binding (PREB), mRNA. Customized vector In-stock 5-7 Starting from $99
OHu35241C XM_006711914 PREDICTED: Homo sapiens prolactin regulatory element binding (PREB), transcript variant X1, mRNA. Customized vector On-demand 7-9 Starting from $99

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Gene Symbol PREB
Entrez Gene ID 10113
Full Name prolactin regulatory element binding
Synonyms SEC12
General protein information
Preferred Names
prolactin regulatory element-binding protein
prolactin regulatory element-binding protein
prolactin regulatory binding-element protein
mammalian guanine nucleotide exchange factor mSec12
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008].

MIM: 606395

mRNA Protein Product Sequence Price Select
NM_013388, 41349447 NP_037520, 7019503 prolactin regulatory element-binding protein ORF Sequence $360.00
XM_006711914, 578802648 XP_006711977, 578802649 prolactin regulatory element-binding protein isoform X1 ORF Sequence $400.00
hsa04141Protein processing in endoplasmic reticulum
REACT_18356Unfolded Protein Response (UPR)
REACT_18368IRE1alpha activates chaperones
REACT_12507COPII (Coat Protein 2) Mediated Vesicle Transport
REACT_11203ER to Golgi Transport
REACT_11123Membrane Trafficking
REACT_17015Metabolism of proteins
REACT_22161Post-translational protein modification
REACT_22426Asparagine N-linked glycosylation
REACT_25046Transport to the Golgi and subsequent modification
REACT_18273XBP1(S) activates chaperone genes
Homo sapiens (human)PREBNP_037520.1
Pan troglodytes (chimpanzee)PREBXP_515352.3
Macaca mulatta (Rhesus monkey)PREBXP_001088763.2
Canis lupus familiaris (dog)PREBXP_540122.2
Bos taurus (cattle)PREBNP_001070343.2
Mus musculus (house mouse)PrebNP_057912.2
Rattus norvegicus (Norway rat)PrebNP_001164179.1
Gallus gallus (chicken)PREBXP_003643564.1
Danio rerio (zebrafish)prebNP_001002638.1
Drosophila melanogaster (fruit fly)CG9175NP_608995.2
Caenorhabditis eleganssec-12NP_492305.2
Xenopus (Silurana) tropicalis (western clawed frog)prebNP_001001231.1
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedIEA
GO:0006888ER to Golgi vesicle-mediated transportTAS
GO:0006987activation of signaling protein activity involved in unfolded protein responseTAS
GO:0015031protein transportIEA
GO:0018279protein N-linked glycosylation via asparagineTAS
GO:0030968endoplasmic reticulum unfolded protein responseTAS
GO:0043687post-translational protein modificationTAS
GO:0044267cellular protein metabolic processTAS
GO:0048208COPII vesicle coatingTAS
GO:0061024membrane organizationTAS
GO:0000139Golgi membraneTAS
GO:0005789endoplasmic reticulum membraneTAS
GO:0016021integral component of membraneIEA
GO:0003677DNA bindingIEA
GeneCards PREB
UniProt B5MC98, Q9HCU5
Vega OTTHUMG00000097076
MIM 606395
Ensembl ENSG00000138073
HGNC 9356
HPRD 16216

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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