CDK3 cyclin-dependent kinase 3 [Homo sapiens (human)]
| Gene Symbol | CDK3 |
| Entrez Gene ID | 1018 |
| Full Name | cyclin-dependent kinase 3 |
| Synonyms | |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
17 17q22-qter |
| Summary | This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq]. |
| Disorder | MIM: 123828 |
| mRNA | NM_001258, 164519034 |
| Protein | NP_001249, 4557439 |
| Product | cyclin-dependent kinase 3 |
| RefSeq Status | VALIDATED |
| Homo sapiens (human) | CDK3 | NP_001249.1 |
| Pan troglodytes (chimpanzee) | CDK3 | XP_001149644.1 |
| Canis lupus familiaris (dog) | CDK3 | XP_540442.2 |
| Bos taurus (cattle) | CDK3 | NP_001092648.1 |
| Gallus gallus (chicken) | CDK3 | XP_427196.2 |
| ID | Name | Evidence |
| GO:0006468 | protein phosphorylation | IEA |
| GO:0007049 | cell cycle | TAS |
| GO:0007067 | mitosis | IEA |
| GO:0008283 | cell proliferation | TAS |
| GO:0051301 | cell division | IEA |
Function
| ID | Name | Evidence |
| GO:0000166 | nucleotide binding | IEA |
| GO:0004693 | cyclin-dependent protein kinase activity | IEA |
| GO:0005524 | ATP binding | IEA |
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