• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


CDK5 cyclin-dependent kinase 5 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu12814 NM_004935 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu12869 NM_001164410 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu12814C NM_004935 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu12869C NM_001164410 Homo sapiens cyclin-dependent kinase 5 (CDK5), transcript variant 2, mRNA. Customized vector On-demand 7-9 $209.00

*Business Day

Related Services

Gene Symbol CDK5
Entrez Gene ID 1020
Full Name cyclin-dependent kinase 5
Synonyms PSSALRE
General protein information
Preferred Names
cyclin-dependent kinase 5
Names
cyclin-dependent kinase 5
TPKII catalytic subunit
protein kinase CDK5 splicing
cell division protein kinase 5
serine/threonine-protein kinase PSSALRE
tau protein kinase II catalytic subunit
NP_001157882.1
NP_004926.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q36

Summary
Disorder

MIM: 123831

mRNA Protein Product Sequence Price Select
NM_001164410, 256542305 NP_001157882, 256542306 cyclin-dependent kinase 5 isoform 2 ORF Sequence $300.00
NM_004935, 256574768 NP_004926, 4826675 cyclin-dependent kinase 5 isoform 1 ORF Sequence $199.00
KEGG
hsa04360Axon guidance
hsa05010Alzheimer's disease
hsa05030Cocaine addiction
WikiPathways
WP707DNA damage response
WP1602Nicotine Activity on Dopaminergic Neurons
WP364IL-6 Signaling Pathway
WP2380BDNF signaling pathway
WP2059Alzheimers Disease
Pathway Interaction Database
reelinpathwayReelin signaling pathway
reg_gr_pathwayGlucocorticoid receptor regulatory network
epha_fwdpathwayEPHA forward signaling
mapktrkpathwayTrk receptor signaling mediated by the MAPK pathway
lis1pathwayLissencephaly gene (LIS1) in neuronal migration and development
Reactome
REACT_18266Axon guidance
REACT_19199CRMPs in Sema3A signaling
REACT_19271Semaphorin interactions
REACT_604Hemostasis
REACT_14797Signaling by GPCR
REACT_15295Opioid Signalling
REACT_15334DARPP-32 events
REACT_24970Factors involved in megakaryocyte development and platelet production
REACT_111102Signal Transduction
REACT_111045Developmental Biology
Homo sapiens (human)CDK5NP_004926.1
Pan troglodytes (chimpanzee)CDK5XP_519523.2
Macaca mulatta (Rhesus monkey)CDK5XP_001102523.1
Canis lupus familiaris (dog)CDK5XP_005629809.1
Bos taurus (cattle)CDK5NP_776442.1
Mus musculus (house mouse)Cdk5NP_031694.1
Rattus norvegicus (Norway rat)Cdk5NP_543161.1
Gallus gallus (chicken)CDK5NP_001129258.1
Danio rerio (zebrafish)cdk5NP_571794.1
Drosophila melanogaster (fruit fly)Cdk5NP_477080.1
Caenorhabditis eleganscdk-5NP_499783.1
Xenopus (Silurana) tropicalis (western clawed frog)cdk5NP_001072776.1
Process
IDNameEvidence
GO:0001764neuron migrationTAS
GO:0001963synaptic transmission, dopaminergicIEA
GO:0006886intracellular protein transportIEA
GO:0006913nucleocytoplasmic transportIEA
GO:0007049cell cycleIEA
GO:0007160cell-matrix adhesionIEA
GO:0007268synaptic transmissionTAS
GO:0007411axon guidanceTAS
GO:0007416synapse assemblyTAS
GO:0007519skeletal muscle tissue developmentIEA
GO:0007596blood coagulationTAS
GO:0008045motor neuron axon guidanceIEA
GO:0008283cell proliferationTAS
GO:0008542visual learningIEA
GO:0009790embryo developmentISS
GO:0014044Schwann cell developmentIEA
GO:0016079synaptic vesicle exocytosisTAS
GO:0016310phosphorylationIDA
GO:0018105peptidyl-serine phosphorylationIDA
GO:0018107peptidyl-threonine phosphorylationIEA
GO:0019233sensory perception of painIEA
GO:0021697cerebellar cortex formationIEA
GO:0021766hippocampus developmentIEA
GO:0021819layer formation in cerebral cortexIEA
GO:0021954central nervous system neuron developmentIEA
GO:0022038corpus callosum developmentIEA
GO:0030182neuron differentiationISS
GO:0030182neuron differentiationTAS
GO:0030334regulation of cell migrationIEA
GO:0030517negative regulation of axon extensionIEA
GO:0030866cortical actin cytoskeleton organizationIEA
GO:0031175neuron projection developmentISS
GO:0031397negative regulation of protein ubiquitinationIEA
GO:0031914negative regulation of synaptic plasticityIEA
GO:0032092positive regulation of protein bindingIEA
GO:0032801receptor catabolic processIEA
GO:0033136serine phosphorylation of STAT3 proteinIEA
GO:0035249synaptic transmission, glutamatergicIEA
GO:0035418protein localization to synapseIEA
GO:0042981regulation of apoptotic processTAS
GO:0043113receptor clusteringIEA
GO:0043525positive regulation of neuron apoptotic processISS
GO:0045055regulated secretory pathwayIEA
GO:0045786negative regulation of cell cycleIEA
GO:0045860positive regulation of protein kinase activityIEA
GO:0045861negative regulation of proteolysisIMP
GO:0045892negative regulation of transcription, DNA-templatedIMP
GO:0045956positive regulation of calcium ion-dependent exocytosisIEA
GO:0046777protein autophosphorylationIEA
GO:0046826negative regulation of protein export from nucleusIEA
GO:0048148behavioral response to cocaineIEA
GO:0048167regulation of synaptic plasticityISS
GO:0048167regulation of synaptic plasticityTAS
GO:0048488synaptic vesicle endocytosisTAS
GO:0048511rhythmic processIEA
GO:0048675axon extensionTAS
GO:0048709oligodendrocyte differentiationIDA
GO:0048813dendrite morphogenesisIEA
GO:0051301cell divisionIEA
GO:0051402neuron apoptotic processTAS
GO:0060079regulation of excitatory postsynaptic membrane potentialIEA
GO:0061001regulation of dendritic spine morphogenesisISS
GO:0070509calcium ion importIEA
GO:0071156regulation of cell cycle arrestTAS
GO:0090314positive regulation of protein targeting to membraneIEA
GO:1901215negative regulation of neuron deathIDA
GO:2000251positive regulation of actin cytoskeleton reorganizationTAS
GO:2000273positive regulation of receptor activityIEA
GO:2000273positive regulation of receptor activityISS
Component
IDNameEvidence
GO:0005634nucleusISS
GO:0005737cytoplasmISS
GO:0005829cytosolTAS
GO:0014069postsynaptic densityISS
GO:0016020membraneISS
GO:0016533cyclin-dependent protein kinase 5 holoenzyme complexIEA
GO:0030027lamellipodiumIEA
GO:0030054cell junctionIEA
GO:0030175filopodiumIEA
GO:0030424axonISS
GO:0030425dendriteISS
GO:0030426growth coneISS
GO:0031594neuromuscular junctionISS
GO:0043025neuronal cell bodyISS
GO:0043204perikaryonIEA
GO:0045211postsynaptic membraneIEA
Function
IDNameEvidence
GO:0002039p53 bindingIEA
GO:0004672protein kinase activityTAS
GO:0004674protein serine/threonine kinase activityIDA
GO:0004674protein serine/threonine kinase activityISS
GO:0004674protein serine/threonine kinase activityTAS
GO:0004693cyclin-dependent protein serine/threonine kinase activityIEA
GO:0005176ErbB-2 class receptor bindingISS
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GO:0016301kinase activityISS
GO:0030549acetylcholine receptor activator activityISS
GO:0043125ErbB-3 class receptor bindingISS
GO:0046875ephrin receptor bindingIEA
GO:0050321tau-protein kinase activityISS
GeneCards CDK5
UniProt Q00535
MIM 123831
HGNC 1774
HPRD 00449

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.