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CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000076 Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001122630 Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001122631 Homo sapiens cyclin-dependent kinase inhibitor 1C (p57, Kip2) (CDKN1C), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol CDKN1C
Entrez Gene ID 1028
Full Name cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Synonyms BWCR, BWS, KIP2, WBS, p57
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.5

Summary This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010].
Disorder

MIM: 600856

Beckwith-Wiedemann syndrome, 130650 (3)

mRNA Protein Product Sequence Price Select
NM_000076, 169790897 NP_000067, 4557441 cyclin-dependent kinase inhibitor 1C isoform a ORF Sequence $400.00
NM_001122630, 169790898 NP_001116102, 169790899 cyclin-dependent kinase inhibitor 1C isoform b ORF Sequence $300.00
NM_001122631, 169790902 NP_001116103, 169790903 cyclin-dependent kinase inhibitor 1C isoform b ORF Sequence $300.00
KEGG
hsa04110Cell cycle
WikiPathways
WP474Endochondral Ossification
WP45G1 to S cell cycle control
Homo sapiens (human)CDKN1CNP_000067.1
Macaca mulatta (Rhesus monkey)CDKN1CXP_001117302.2
Bos taurus (cattle)CDKN1CNP_001071371.1
Mus musculus (house mouse)Cdkn1cNP_001155096.1
Rattus norvegicus (Norway rat)Cdkn1cNP_001028930.1
Danio rerio (zebrafish)cdkn1cNP_001002040.1
GeneCards CDKN1C
UniProt P49918
MIM 600856
Ensembl ENSG00000129757
HGNC 1786
HPRD 02913

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
cyclin-dependent kinase inhibitor 1C
Names
cyclin-dependent kinase inhibitor 1C
cyclin-dependent kinase inhibitor p57

Interactant



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