CLEC10A C-type lectin domain family 10, member A [Homo sapiens (human)]
| Gene Symbol | CLEC10A |
| Entrez Gene ID | 10462 |
| Full Name | C-type lectin domain family 10, member A |
| Synonyms | CD301, CLECSF13, CLECSF14, HML, HML2, MGL |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
17 17p13.1 |
| Summary | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq]. |
| Disorder | MIM: 605999 |
| mRNA | NM_006344, 53832015 |
| Protein | NP_006335, 53832016 |
| Product | C-type lectin domain family 10 member A isoform 2 |
| RefSeq Status | REVIEWED |
| mRNA | NM_182906, 53832017 |
| Protein | NP_878910, 33667103 |
| Product | C-type lectin domain family 10 member A isoform 1 |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | CLEC10A | NP_006335.2 |
| Pan troglodytes (chimpanzee) | CLEC10A | XP_001168677.1 |
| Canis lupus familiaris (dog) | CLEC10A | XP_856984.1 |
| Mus musculus (house mouse) | Mgl2 | NP_660119.1 |
| Mus musculus (house mouse) | Clec10a | NP_034926.1 |
| Rattus norvegicus (Norway rat) | Clec10a | NP_071788.2 |
| ID | Name | Evidence |
| GO:0006897 | endocytosis | IEA |
| GO:0045087 | innate immune response | IEA |
Component
| ID | Name | Evidence |
| GO:0005886 | plasma membrane | TAS |
| GO:0016021 | integral to membrane | IEA |
Function
| ID | Name | Evidence |
| GO:0005488 | binding | IEA |
| GO:0005529 | sugar binding | IEA |
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