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CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu27253 NM_001805 Homo sapiens CCAAT/enhancer binding protein (C/EBP), epsilon (CEBPE), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu27253C NM_001805 Homo sapiens CCAAT/enhancer binding protein (C/EBP), epsilon (CEBPE), mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol CEBPE
Entrez Gene ID 1053
Full Name CCAAT/enhancer binding protein (C/EBP), epsilon
Synonyms C/EBP-epsilon, CRP1
General protein information
Preferred Names
CCAAT/enhancer-binding protein epsilon
Names
CCAAT/enhancer-binding protein epsilon
c/EBP epsilon
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q11.2

Summary The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600749

Specific granule deficiency, 245480 (3)

mRNA Protein Product Sequence Price Select
NM_001805, 356640246 NP_001796, 28872800 CCAAT/enhancer-binding protein epsilon ORF Sequence $199.00
KEGG
hsa05202Transcriptional misregulation in cancer
Homo sapiens (human)CEBPENP_001796.2
Pan troglodytes (chimpanzee)CEBPEXP_001161080.2
Macaca mulatta (Rhesus monkey)CEBPEXP_001106328.1
Canis lupus familiaris (dog)CEBPEXP_547729.1
Bos taurus (cattle)CEBPENP_001179737.1
Mus musculus (house mouse)CebpeNP_997014.1
Rattus norvegicus (Norway rat)CebpeNP_058791.1
Xenopus (Silurana) tropicalis (western clawed frog)cebpeXP_002939064.1
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0006909phagocytosisIEA
GO:0006952defense responseTAS
GO:0030225macrophage differentiationIEA
GO:0042089cytokine biosynthetic processIEA
GO:0042742defense response to bacteriumIEA
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA
GO:0071222cellular response to lipopolysaccharideIEA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
Function
IDNameEvidence
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingIDA
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIDA
GO:0042803protein homodimerization activityIEA
GO:0046982protein heterodimerization activityIEA
GeneCards CEBPE
PDB 3T92
UniProt Q15744
Vega OTTHUMG00000028719
MIM 600749
Ensembl ENSG00000092067
HGNC 1836
HPRD 02852

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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