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Sequence in raw or FASTA format:


Blast Method:


AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001012727 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $399.00 14
NM_006412 Homo sapiens 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $449.00 14

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Gene Symbol AGPAT2
Entrez Gene ID 10555
Full Name 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
Synonyms 1-AGPAT2, BSCL, BSCL1, LPAAB, LPAAT-beta
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

MIM: 603100

Lipodystrophy, congenital generalized, type 1, 608594 (3)

mRNA Protein Product Sequence Price Select
NM_001012727, 69122970 NP_001012745, 69122971 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform b precursor ORF Sequence $250.00
NM_006412, 68835055 NP_006403, 6041665 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform a ORF Sequence $300.00
hsa00561Glycerolipid metabolism
hsa_M00089Triacylglycerol biosynthesis
hsa04975Fat digestion and absorption
hsa00564Glycerophospholipid metabolism
WP2256Integrated Pancreatic Cancer Pathway
WP2377Integrated Pancreatic Cancer Pathway
WP325Triacylglyceride Synthesis
META_PWY-5667CDP-diacylglycerol biosynthesis I
HUMAN_PWY-5667CDP-diacylglycerol biosynthesis I
HUMAN_PWY4FS-8phosphatidylglycerol biosynthesis II (non-plastidic)
HUMAN_TRIGLSYN-PWYtriacylglycerol biosynthesis
REACT_1190Triglyceride Biosynthesis
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_120870Phospholipid metabolism
REACT_120906Synthesis of PA
REACT_121401Glycerophospholipid biosynthesis
Homo sapiens (human)AGPAT2NP_006403.2
Pan troglodytes (chimpanzee)AGPAT2XP_001162511.3
Macaca mulatta (Rhesus monkey)AGPAT2XP_001094500.1
Canis lupus familiaris (dog)AGPAT2XP_548370.4
Bos taurus (cattle)AGPAT2NP_001073733.1
Mus musculus (house mouse)Agpat2NP_080488.1
Rattus norvegicus (Norway rat)Agpat2NP_001101291.1
Gallus gallus (chicken)AGPAT2XP_001235300.2
GeneCards AGPAT2
UniProt O15120
MIM 603100
Ensembl ENSG00000169692
HGNC 325
HPRD 04373

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
1-acyl-sn-glycerol-3-phosphate acyltransferase beta
1-AGP acyltransferase 2
lysophosphatidic acid acyltransferase beta
lysophosphatidic acid acyltransferase-beta
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)


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