LBX1 ladybird homeobox 1 [Homo sapiens (human)]
| Gene Symbol | LBX1 |
| Entrez Gene ID | 10660 |
| Full Name | ladybird homeobox 1 |
| Synonyms | HPX-6, HPX6, LBX1H, homeobox |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
10 10q24 |
| Summary | This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq]. COMPLETENESS: full length. |
| Disorder | MIM: 604255 |
| mRNA | NM_006562, 63054871 |
| Protein | NP_006553, 63054872 |
| Product | transcription factor LBX1 |
| RefSeq Status | REVIEWED |
| Homo sapiens (human) | LBX1 | NP_006553.2 |
| Pan troglodytes (chimpanzee) | LBX1 | XP_521589.1 |
| Canis lupus familiaris (dog) | LBX1 | XP_543979.1 |
| Bos taurus (cattle) | LBX1 | XP_614245.3 |
| Mus musculus (house mouse) | Lbx1 | NP_034821.2 |
| Rattus norvegicus (Norway rat) | Lbx1 | XP_574675.2 |
| Danio rerio (zebrafish) | lbx1b | NP_001020703.1 |
| ID | Name | Evidence |
| GO:0001947 | heart looping | IEA |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA |
| GO:0007275 | multicellular organismal development | IEA |
| GO:0007399 | nervous system development | IEA |
| GO:0007517 | muscle organ development | IEA |
| GO:0008285 | negative regulation of cell proliferation | IEA |
| GO:0009653 | anatomical structure morphogenesis | TAS |
| GO:0021920 | regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification | IEA |
| GO:0030154 | cell differentiation | IEA |
| GO:0045665 | negative regulation of neuron differentiation | IEA |
| GO:0048664 | neuron fate determination | IEA |
Component
| ID | Name | Evidence |
| GO:0005634 | nucleus | IEA |
| GO:0005667 | transcription factor complex | IEA |
Function
| ID | Name | Evidence |
| GO:0003700 | sequence-specific DNA binding transcription factor activity | IEA |
| GO:0043565 | sequence-specific DNA binding | IEA |
Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.
 |
Secured Online Quotation |
 |
Email: gene@genscript.com |
 |
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188 |
 |
Fax: 1-732-210-0262 1-732-885-5878 |