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TRAF3IP2 TRAF3 interacting protein 2 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001164281 Homo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 3, mRNA. GenEZ ORF Cloning On-demand $699.00 18
NM_001164283 Homo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 5, mRNA. GenEZ ORF Cloning On-demand $299.00 14
NM_147686 Homo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol TRAF3IP2
Entrez Gene ID 10758
Full Name TRAF3 interacting protein 2
Synonyms ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

6

6q21

Summary This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq, Aug 2009].
Disorder

MIM: 607043

mRNA Protein Product Sequence Price Select
NM_001164281, 373938459 NP_001157753, 256017209 adapter protein CIKS isoform 3 ORF Sequence $550.00
NM_001164283, 373938460 NP_001157755, 256017213 adapter protein CIKS isoform 5 ORF Sequence $150.00
NM_147686, 373938458 NP_679211, 256017207 adapter protein CIKS isoform 2 ORF Sequence $550.00
Homo sapiens (human)TRAF3IP2NP_679211.2
Pan troglodytes (chimpanzee)TRAF3IP2XP_001157429.2
Macaca mulatta (Rhesus monkey)TRAF3IP2XP_001086102.2
Canis lupus familiaris (dog)TRAF3IP2XP_532266.3
Bos taurus (cattle)TRAF3IP2NP_001030560.1
Mus musculus (house mouse)Traf3ip2NP_598761.2
Rattus norvegicus (Norway rat)Traf3ip2NP_001037713.1
Gallus gallus (chicken)TRAF3IP2XP_419782.1
GeneCards TRAF3IP2
UniProt O43734, Q7Z6Q1
MIM 607043
Ensembl ENSG00000056972
HGNC 1343
HPRD 06129

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
adapter protein CIKS
Names
adapter protein CIKS
NFkB-activating protein ACT1
connection to IKK and SAPK/JNK
nuclear factor NF-kappa-B activator 1

Interactant



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