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SPINK5 serine peptidase inhibitor, Kazal type 5 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001127698 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 1, mRNA. ORF Sequence $1149.75
Peptide Services
Antibody Services
Protein Services
NM_001127699 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 3, mRNA. ORF Sequence $797.79
Peptide Services
Antibody Services
Protein Services
NM_006846 Homo sapiens serine peptidase inhibitor, Kazal type 5 (SPINK5), transcript variant 2, mRNA. ORF Sequence $1118.25
Peptide Services
Antibody Services
Protein Services


Gene Symbol SPINK5
Entrez Gene ID 11005
Full Name serine peptidase inhibitor, Kazal type 5
Synonyms DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q32

Summary This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 605010

Netherton syndrome, 256500 (3); Atopy, 147050 (3)

mRNA Protein Product Sequence Price Select
NM_001127698, 189163500 NP_001121170, 189163501 serine protease inhibitor Kazal-type 5 isoform a precursor Full Length $1310.75
ORF Sequence $1149.75
NM_001127699, 189163503 NP_001121171, 189163504 serine protease inhibitor Kazal-type 5 isoform c precursor Full Length $845.35
ORF Sequence $797.79
NM_006846, 189163502 NP_006837, 74027261 serine protease inhibitor Kazal-type 5 isoform b precursor Full Length $1279.25
ORF Sequence $1118.25
Homo sapiens (human)SPINK5NP_006837.2
Pan troglodytes (chimpanzee)SPINK5XP_001160674.1
Macaca mulatta (Rhesus monkey)SPINK5XP_001103296.1
Canis lupus familiaris (dog)SPINK5NP_001020568.1
Bos taurus (cattle)SPINK5NP_001095572.1
Mus musculus (house mouse)Spink5NP_001074649.1
Rattus norvegicus (Norway rat)Spink5XP_341608.4
Gallus gallus (chicken)SPINK5NP_001025783.1
GeneCards SPINK5
PDB 1HDL, 1UVG, 1H0Z, 1UVF, 1UUC
UniProt Q9NQ38
MIM 605010
Ensembl ENSG00000133710
HGNC 15464
HPRD 05423

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
serine protease inhibitor Kazal-type 5
Names
serine protease inhibitor Kazal-type 5
serine protease inhibitor, Kazal type 5
lymphoepithelial Kazal-type-related inhibitor
lympho-epithelial Kazal-type-related inhibitor

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