• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_139025 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 1, mRNA. ORF Sequence $1499.40
Peptide Services
Antibody Services
Protein Services
NM_139026 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 3, mRNA. ORF Sequence $1408.05
Peptide Services
Antibody Services
Protein Services
NM_139027 Homo sapiens ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13), transcript variant 2, mRNA. ORF Sequence $1440.60
Peptide Services
Antibody Services
Protein Services


Gene Symbol ADAMTS13
Entrez Gene ID 11093
Full Name ADAM metallopeptidase with thrombospondin type 1 motif, 13
Synonyms C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, VWFCP, vWF-CP
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9q34

Summary This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2008].
Disorder

MIM: 604134

Thrombotic thrombocytopenic purpura, familial, 274150 (3)

mRNA Protein Product Sequence Price Select
NM_139025, 190881474 NP_620594, 21265034 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 1 preproprotein Full Length $1729.35
ORF Sequence $1499.40
NM_139026, 190881476 NP_620595, 21265043 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 3 preproprotein Full Length $1638.00
ORF Sequence $1408.05
NM_139027, 190881475 NP_620596, 73695936 A disintegrin and metalloproteinase with thrombospondin motifs 13 isoform 2 preproprotein Full Length $1670.55
ORF Sequence $1440.60
Homo sapiens (human)ADAMTS13NP_620594.1
Pan troglodytes (chimpanzee)ADAMTS13XP_003312433.1
Canis lupus familiaris (dog)ADAMTS13NP_001229641.1
Bos taurus (cattle)ADAMTS13XP_002691670.1
Mus musculus (house mouse)Adamts13NP_001001322.1
Gallus gallus (chicken)ADAMTS13XP_415435.3
Danio rerio (zebrafish)adamts13XP_002663267.2
GeneCards ADAMTS13
PDB 3GHN, 3GHM, 3VN4
UniProt Q76LX8, B3KWF7
MIM 604134
Ensembl ENSG00000160323
HGNC 1366
HPRD 04994

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 13
Names
A disintegrin and metalloproteinase with thrombospondin motifs 13
vWF-cleaving protease
von Willebrand factor-cleaving protease
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
NP_620594.1
NP_620595.1
NP_620596.2

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Secured Online Quotation
Email: gene@genscript.com
Phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
Fax: 1-732-210-0262 1-732-885-5878