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ADCY6 adenylate cyclase 6 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_015270 Homo sapiens adenylate cyclase 6 (ADCY6), transcript variant 1, mRNA. ORF Sequence $1227.45
Peptide Services
Antibody Services
Protein Services
NM_020983 Homo sapiens adenylate cyclase 6 (ADCY6), transcript variant 2, mRNA. ORF Sequence $1171.80
Peptide Services
Antibody Services
Protein Services


Gene Symbol ADCY6
Entrez Gene ID 112
Full Name adenylate cyclase 6
Synonyms AC6, DKFZp779F075, KIAA0422
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12q12-q13

Summary This gene encodes adenylate cyclase 6, which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). The expression of this gene is found in normal thyroid and brain tissues, as well as some tumors; and its expression is significantly higher in one hyperfunctioning thyroid tumor than in normal thyroid tissue. Alternative splicing generates 2 transcript variants. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600294

mRNA Protein Product Sequence Price Select
NM_015270, 168480141 NP_056085, 10181096 adenylate cyclase type 6 isoform a Full Length $2962.35
ORF Sequence $1227.45
NM_020983, 21071019 NP_066193, 10947061 adenylate cyclase type 6 isoform b Full Length $2644.65
ORF Sequence $1171.80
KEGG
hsa04270Vascular smooth muscle contraction
hsa05166HTLV-I infection
hsa04724Glutamatergic synapse
hsa05032Morphine addiction
hsa04914Progesterone-mediated oocyte maturation
hsa05414Dilated cardiomyopathy
hsa04972Pancreatic secretion
hsa04742Taste transduction
hsa04713Circadian entrainment
hsa00230Purine metabolism
hsa04916Melanogenesis
hsa04976Bile secretion
hsa04971Gastric acid secretion
hsa04961Endocrine and other factor-regulated calcium reabsorption
hsa04723Retrograde endocannabinoid signaling
hsa04540Gap junction
hsa04970Salivary secretion
hsa04062Chemokine signaling pathway
hsa04727GABAergic synapse
hsa04962Vasopressin-regulated water reabsorption
hsa04114Oocyte meiosis
hsa04912GnRH signaling pathway
hsa04725Cholinergic synapse
Pathway Interaction Database
endothelinpathwayEndothelins
lysophospholipid_pathwayLPA receptor mediated events
lpa4_pathwayLPA4-mediated signaling events
WikiPathways
WP536Calcium Regulation in the Cardiac Cell
WP35G Protein Signaling Pathways
WP289Myometrial Relaxation and Contraction Pathways
Reactome
REACT_21310Phospholipase C-mediated cascade
REACT_15518Transmembrane transport of small molecules
REACT_14797Signaling by GPCR
REACT_1946PKA activation in glucagon signalling
REACT_15497PKA-mediated phosphorylation of CREB
REACT_12079PLC-gamma1 signalling
REACT_16888Signaling by PDGF
REACT_21272Downstream signaling of activated FGFR
REACT_18325Regulation of Insulin Secretion
REACT_9000Calmodulin induced events
REACT_23887Aquaporin-mediated transport
REACT_15333Adenylate cyclase inhibitory pathway
REACT_115871Signaling by EGFR in Cancer
REACT_9053CaM pathway
REACT_13685Neuronal System
REACT_25330Activation of GABAB receptors
REACT_17025Downstream signal transduction
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_19327G alpha (s) signalling events
REACT_19333G alpha (z) signalling events
REACT_18339Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
REACT_115755Signaling by ERBB2
REACT_24023Regulation of Water Balance by Renal Aquaporins
REACT_1665Glucagon signaling in metabolic regulation
REACT_15295Opioid Signalling
REACT_18274Regulation of Insulin Secretion by Glucagon-like Peptide-1
REACT_111064DAG and IP3 signaling
REACT_13477Transmission across Chemical Synapses
REACT_25282Inhibition of adenylate cyclase pathway
REACT_9470Signaling by FGFR
REACT_15312Adenylate cyclase activating pathway
REACT_116125Disease
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_25199GABA receptor activation
REACT_6900Immune System
REACT_115720PLCG1 events in ERBB2 signaling
REACT_147694DAP12 interactions
REACT_25031GABA B receptor activation
REACT_15526G-protein mediated events
REACT_15307Ca-dependent events
REACT_12478EGFR interacts with phospholipase C-gamma
REACT_147814DAP12 signaling
REACT_15426PLC beta mediated events
REACT_9417Signaling by EGFR
REACT_19231G alpha (i) signalling events
REACT_6802Innate Immune System
REACT_111217Metabolism
REACT_11061Signalling by NGF
REACT_1505Integration of energy metabolism
REACT_111102Signal Transduction
REACT_120736Signaling by FGFR in disease
REACT_19184GPCR downstream signaling
REACT_15530PKA activation
Homo sapiens (human)ADCY6NP_056085.1
Pan troglodytes (chimpanzee)ADCY6XP_509033.3
Macaca mulatta (Rhesus monkey)ADCY6XP_001102486.1
Canis lupus familiaris (dog)ADCY6NP_001182076.1
Bos taurus (cattle)ADCY6NP_001137349.1
Mus musculus (house mouse)Adcy6NP_031431.2
Rattus norvegicus (Norway rat)Adcy6NP_036953.2
Danio rerio (zebrafish)adcy6bXP_002666536.1
Danio rerio (zebrafish)adcy6aXP_001922749.1
GeneCards ADCY6
UniProt O43306
MIM 600294
Ensembl ENSG00000174233
HGNC 237
HPRD 02621

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
adenylate cyclase type 6
Names
adenylate cyclase type 6
adenylyl cyclase 6
ATP pyrophosphate-lyase 6
adenylate cyclase type VI
ca(2+)-inhibitable adenylyl cyclase
NP_056085.1
NP_066193.1

Interactant

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