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POU6F2 POU class 6 homeobox 2 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001166018 Homo sapiens POU class 6 homeobox 2 (POU6F2), transcript variant 2, mRNA. ORF Sequence $570.72
Peptide Services
Antibody Services
Protein Services
NM_007252 Homo sapiens POU class 6 homeobox 2 (POU6F2), transcript variant 1, mRNA. ORF Sequence $602.04
Peptide Services
Antibody Services
Protein Services


Gene Symbol POU6F2
Entrez Gene ID 11281
Full Name POU class 6 homeobox 2
Synonyms RPF-1, WT5, WTSL
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7p14.1

Summary This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
Disorder

MIM: 609062

{Wilms tumor susceptibility-5}, 601583 (3)

mRNA Protein Product Sequence Price Select
NM_001166018, 260436857 NP_001159490, 260436858 POU domain, class 6, transcription factor 2 isoform 2 Full Length $642.64
ORF Sequence $570.72
NM_007252, 260436856 NP_009183, 157743257 POU domain, class 6, transcription factor 2 isoform 1 Full Length $673.96
ORF Sequence $602.04
Homo sapiens (human)POU6F2NP_009183.3
Pan troglodytes (chimpanzee)POU6F2XP_527726.2
Canis lupus familiaris (dog)POU6F2XP_540368.4
Bos taurus (cattle)POU6F2NP_001095516.1
Mus musculus (house mouse)Pou6f2NP_778171.2
Gallus gallus (chicken)POU6F2XP_418861.2
Drosophila melanogaster (fruit fly)pdm3NP_001137617.2
GeneCards POU6F2
UniProt P78424
MIM 609062
Ensembl ENSG00000106536
HGNC 21694
HPRD 10162

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
POU domain, class 6, transcription factor 2
Names
POU domain, class 6, transcription factor 2
Wilms tumor suppressor locus
retina-derived POU domain factor 1
retina-derived POU-domain factor-1

Interactant

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