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PARK7 Parkinson disease (autosomal recessive, early onset) 7 [Homo sapiens (human)]

RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001123377 Homo sapiens parkinson protein 7 (PARK7), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $399.00 14
NM_007262 Homo sapiens parkinson protein 7 (PARK7), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $399.00 14

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Gene Symbol PARK7
Entrez Gene ID 11315
Full Name Parkinson disease (autosomal recessive, early onset) 7
Synonyms DJ-1, DJ1, FLJ27376, FLJ34360, FLJ92274
Gene Type protein-coding
Organism Homo sapiens (human)



Summary The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].

MIM: 602533

Parkinson disease 7, autosomal recessive early-onset, 606324 (3);

mRNA Protein Product Sequence Price Select
NM_001123377, 183227677 NP_001116849, 183227678 protein DJ-1 ORF Sequence $250.00
NM_007262, 183227676 NP_009193, 31543380 protein DJ-1 ORF Sequence $250.00
hsa05012Parkinson's disease
Pathway Interaction Database
alphasynuclein_pathwayAlpha-synuclein signaling
WP2371Parkinsons Disease Pathway
WP2267Synaptic Vesicle Pathway
WP138Androgen receptor signaling pathway
Homo sapiens (human)PARK7NP_001116849.1
Pan troglodytes (chimpanzee)PARK7XP_001158489.1
Canis lupus familiaris (dog)PARK7XP_536733.1
Bos taurus (cattle)PARK7NP_001015572.1
Mus musculus (house mouse)Park7NP_065594.2
Rattus norvegicus (Norway rat)Park7NP_476484.1
Gallus gallus (chicken)PARK7NP_989916.1
Danio rerio (zebrafish)park7NP_001005938.1
Drosophila melanogaster (fruit fly)dj-1betaNP_651825.3
Drosophila melanogaster (fruit fly)DJ-1alphaNP_610916.1
Caenorhabditis elegansdjr-1.1NP_493696.1
Caenorhabditis elegansdjr-1.2NP_504132.1
GeneCards PARK7
PDB 2OR3, 1UCF, 3BWE, 2R1U, 3EZG, 1SOA, 3CZ9, 2R1V, 3B3A, 3B36, 3SF8, 1Q2U, 1PDW, 1J42, 2RK4, 3CZA, 3B38, 1PDV, 3CYF, 1PE0, 2R1T, 2RK6, 2RK3, 3F71, 3CY6, 1P5F
UniProt Q99497
MIM 602533
Ensembl ENSG00000116288
HGNC 16369
HPRD 03961

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
protein DJ-1
protein DJ-1
oncogene DJ1
Parkinson disease (autosomal recessive, early onset) 7


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