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CKM creatine kinase, muscle [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001824 Homo sapiens creatine kinase, muscle (CKM), mRNA. GenEZ ORF Cloning On-demand $549.00 14
XM_005258497 PREDICTED: Homo sapiens creatine kinase, muscle (CKM), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Related Services

Gene Symbol CKM
Entrez Gene ID 1158
Full Name creatine kinase, muscle
Synonyms CKMM, M-CK
General protein information
Preferred Names
creatine kinase M-type
Names
creatine kinase M-type
creatine kinase M chain
NP_001815.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19q13.32

Summary The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008].
Disorder

MIM: 123310

mRNA Protein Product Sequence Price Select
NM_001824, 388490199 NP_001815, 21536288 creatine kinase M-type ORF Sequence $400.00
XM_005258497, 530415664 XP_005258554, 530415665 creatine kinase M-type isoform X1 ORF Sequence $550.00
KEGG
hsa00330Arginine and proline metabolism
hsa_M00047Creatine pathway
WikiPathways
WP497Urea cycle and metabolism of amino groups
Pathway Interaction Database
rb_1pathwayRegulation of retinoblastoma protein
BIOCYC
META_PWY-6158creatine-phosphate biosynthesis
HUMAN_PWY-6158creatine-phosphate biosynthesis
Reactome
REACT_13Metabolism of amino acids and derivatives
REACT_813Creatine metabolism
REACT_111217Metabolism
Homo sapiens (human)CKMNP_001815.2
Pan troglodytes (chimpanzee)CKMXP_001163660.2
Canis lupus familiaris (dog)CKMXP_005616506.1
Bos taurus (cattle)CKMNP_777198.2
Mus musculus (house mouse)CkmNP_031736.1
Rattus norvegicus (Norway rat)CkmNP_036662.1
Gallus gallus (chicken)CKMNP_990838.1
Danio rerio (zebrafish)ckmbNP_001099153.1
Danio rerio (zebrafish)ckmaNP_571007.1
Xenopus (Silurana) tropicalis (western clawed frog)ckmNP_989374.1
Process
IDNameEvidence
GO:0006600creatine metabolic processTAS
GO:0016310phosphorylationIEA
GO:0034641cellular nitrogen compound metabolic processTAS
GO:0044281small molecule metabolic processTAS
GO:0046314phosphocreatine biosynthetic processIEA
Component
IDNameEvidence
GO:0005829cytosolTAS
Function
IDNameEvidence
GO:0004111creatine kinase activityIEA
GO:0005524ATP bindingIEA
GeneCards CKM
PDB 1I0E
UniProt P06732, B2R892
Vega OTTHUMG00000181782
MIM 123310
Ensembl ENSG00000104879
HGNC 1994
HPRD 00426

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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