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ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001099733 Homo sapiens adenylate cyclase activating polypeptide 1 (pituitary) (ADCYAP1), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand TBD TBD
NM_001117 Homo sapiens adenylate cyclase activating polypeptide 1 (pituitary) (ADCYAP1), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand TBD TBD

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Related Services

Gene Symbol ADCYAP1
Entrez Gene ID 116
Full Name adenylate cyclase activating polypeptide 1 (pituitary)
Synonyms MGC126852, PACAP
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

18

18p11

Summary This gene encodes a secreted proprotein that is further processed into multiple mature peptides. These peptides stimulate adenylate cyclase and increase cyclic adenosine monophosphate (cAMP) levels, resulting in the transcriptional activation of target genes. The products of this gene are key mediators of neuroendocrine stress responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013].
Disorder

MIM: 102980

mRNA Protein Product Sequence Price Select
NM_001099733, 153266791 NP_001093203, 153266792 pituitary adenylate cyclase-activating polypeptide preproprotein ORF Sequence $250.00
NM_001117, 452085176 NP_001108, 153266795 pituitary adenylate cyclase-activating polypeptide preproprotein ORF Sequence $250.00
WikiPathways
WP706SIDS Susceptibility Pathways
Reactome
REACT_18372Class B/2 (Secretin family receptors)
REACT_21340GPCR ligand binding
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_19184GPCR downstream signaling
REACT_11064Activation of TRKA receptors
REACT_111102Signal Transduction
REACT_18377Glucagon-type ligand receptors
REACT_14797Signaling by GPCR
REACT_19327G alpha (s) signalling events
REACT_11061Signalling by NGF
REACT_11046NGF-independant TRKA activation
Homo sapiens (human)ADCYAP1NP_001093203.1
Pan troglodytes (chimpanzee)ADCYAP1NP_001181872.1
Canis lupus familiaris (dog)ADCYAP1XP_849191.2
Bos taurus (cattle)ADCYAP1NP_001040020.1
Mus musculus (house mouse)Adcyap1NP_033755.1
Rattus norvegicus (Norway rat)Adcyap1NP_058685.1
Gallus gallus (chicken)ADCYAP1NP_001001291.2
Danio rerio (zebrafish)adcyap1bNP_999880.1
Danio rerio (zebrafish)adcyap1aNP_690841.1
GeneCards ADCYAP1
PDB 2JOD, 1GEA, 2D2P
UniProt P18509
MIM 102980
Ensembl ENSG00000141433
HGNC 241
HPRD 02369

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
pituitary adenylate cyclase-activating polypeptide
Names
pituitary adenylate cyclase-activating polypeptide
prepro-PACAP

Interactant



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