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APOA5 apolipoprotein A-V [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001166598 Homo sapiens apolipoprotein A-V (APOA5), transcript variant 2, mRNA. GenEZ ORF Cloning On-demand $549.00 14
NM_052968 Homo sapiens apolipoprotein A-V (APOA5), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $549.00 14

*Business Day

Related Services

Gene Symbol APOA5
Entrez Gene ID 116519
Full Name apolipoprotein A-V
Synonyms APOAV, FLJ97995, MGC126836, MGC126838, RAP3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q23

Summary The protein encoded by this gene is an apolipoprotein that plays an important role in regulating the plasma triglyceride levels, a major risk factor for coronary artery disease. It is a component of high density lipoprotein and is highly similar to a rat protein that is upregulated in response to liver injury. Mutations in this gene have been associated with hypertriglyceridemia and hyperlipoproteinemia type 5. This gene is located proximal to the apolipoprotein gene cluster on chromosome 11q23. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Oct 2009].
Disorder

MIM: 606368

{Hypertriglyceridemia, susceptibility to}, 145750 (3);

mRNA Protein Product Sequence Price Select
NM_001166598, 262231736 NP_001160070, 262231737 apolipoprotein A-V precursor ORF Sequence $400.00
NM_052968, 262231738 NP_443200, 63079709 apolipoprotein A-V precursor ORF Sequence $400.00
KEGG
hsa03320PPAR signaling pathway
WikiPathways
WP430Statin Pathway
Reactome
REACT_6823Lipoprotein metabolism
REACT_602Lipid digestion, mobilization, and transport
REACT_116145PPARA Activates Gene Expression
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_6841Chylomicron-mediated lipid transport
REACT_22258Metabolism of lipids and lipoproteins
REACT_19241Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_111217Metabolism
Homo sapiens (human)APOA5NP_001160070.1
Pan troglodytes (chimpanzee)APOA5XP_003313360.1
Macaca mulatta (Rhesus monkey)APOA5XP_001090079.1
Canis lupus familiaris (dog)APOA5XP_546511.1
Bos taurus (cattle)APOA5NP_001076961.1
Mus musculus (house mouse)Apoa5NP_536682.2
Rattus norvegicus (Norway rat)Apoa5NP_542143.1
Gallus gallus (chicken)APOA5XP_417939.2
GeneCards APOA5
UniProt Q6Q788
MIM 606368
Ensembl ENSG00000110243
HGNC 17288
HPRD 06966

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
apolipoprotein A-V
Names
apolipoprotein A-V
apo-AV
apolipoprotein A5
regeneration-associated protein 3

Interactant



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