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GSC goosecoid homeobox [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18704 NM_173849 Homo sapiens goosecoid homeobox (GSC), mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu18704C NM_173849 Homo sapiens goosecoid homeobox (GSC), mRNA. Customized vector On-demand TBD $209.00

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Gene Symbol GSC
Entrez Gene ID 145258
Full Name goosecoid homeobox
Synonyms SAMS
General protein information
Preferred Names
homeobox protein goosecoid
Names
homeobox protein goosecoid
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q32.1

Summary This gene encodes a member of the bicoid subfamily of the paired (PRD) homeobox family of proteins. The encoded protein acts as a transcription factor and may be autoregulatory. A similar protein in mice plays a role in craniofacial and rib cage development during embryogenesis. [provided by RefSeq, Jul 2008].
Disorder

MIM: 138890

mRNA Protein Product Sequence Price Select
NM_173849, 29171761 NP_776248, 27777663 homeobox protein goosecoid ORF Sequence $300.00
Pathway Interaction Database
smad2_3nuclearpathwayRegulation of nuclear SMAD2/3 signaling
rb_1pathwayRegulation of retinoblastoma protein
Homo sapiens (human)GSCNP_776248.1
Pan troglodytes (chimpanzee)GSCNP_001074955.1
Macaca mulatta (Rhesus monkey)GSCXP_001100695.1
Canis lupus familiaris (dog)GSCXP_005623984.1
Bos taurus (cattle)GSCNP_001179315.1
Mus musculus (house mouse)GscNP_034481.1
Rattus norvegicus (Norway rat)GscNP_001178802.1
Gallus gallus (chicken)GSCNP_990662.1
Danio rerio (zebrafish)gscNP_571092.1
Xenopus (Silurana) tropicalis (western clawed frog)gscNP_001016704.1
Process
IDNameEvidence
GO:0000122negative regulation of transcription from RNA polymerase II promoterIEA
GO:0007369gastrulationNAS
GO:0014036neural crest cell fate specificationIMP
GO:0021904dorsal/ventral neural tube patterningIEA
GO:0023019signal transduction involved in regulation of gene expressionIEA
GO:0030178negative regulation of Wnt signaling pathwayIEA
GO:0030900forebrain developmentIEA
GO:0042474middle ear morphogenesisISS
GO:0048644muscle organ morphogenesisIEA
GO:0048704embryonic skeletal system morphogenesisIEA
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005667transcription factor complexIEA
Function
IDNameEvidence
GO:0001085RNA polymerase II transcription factor bindingISS
GO:0001103RNA polymerase II repressing transcription factor bindingISS
GO:0003700sequence-specific DNA binding transcription factor activityIEA
GO:0043565sequence-specific DNA bindingIEA
GeneCards GSC
PDB 2DMU
UniProt P56915
Vega OTTHUMG00000170864
MIM 138890
Ensembl ENSG00000133937
HGNC 4612
HPRD 15928

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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