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DSG4 desmoglein 4 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu22937 NM_177986 Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu31898 NM_001134453 Homo sapiens desmoglein 4 (DSG4), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 25 $1699.00
OHu22937C NM_177986 Homo sapiens desmoglein 4 (DSG4), transcript variant 2, mRNA. Customized vector On-demand 25 $1699.00
OHu31898C NM_001134453 Homo sapiens desmoglein 4 (DSG4), transcript variant 1, mRNA. Customized vector On-demand 25 $1699.00

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Gene Symbol DSG4
Entrez Gene ID 147409
Full Name desmoglein 4
Synonyms CDGF13, CDHF13, HYPT6, LAH
General protein information
Preferred Names
desmoglein-4
Names
desmoglein-4
CDH family member 13
cadherin family member 13
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

18

18q12.1

Summary This gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded protein is a transmembrane component in desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and potentially in other skin disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].
Disorder

MIM: 607892

Hypotrichosis, localized, autosomal recessive, 607903 (3)

mRNA Protein Product Sequence Price Select
NM_001134453, 197313786 NP_001127925, 197313787 desmoglein-4 isoform 1 preproprotein ORF Sequence $1500.00
NM_177986, 259155289 NP_817123, 29789445 desmoglein-4 isoform 2 preproprotein ORF Sequence $1500.00
Homo sapiens (human)DSG4NP_817123.1
Pan troglodytes (chimpanzee)DSG4XP_003953318.1
Macaca mulatta (Rhesus monkey)DSG4XP_001102180.1
Canis lupus familiaris (dog)DSG4XP_005623044.1
Bos taurus (cattle)DSG4XP_002697734.1
Mus musculus (house mouse)Dsg4NP_853543.1
Rattus norvegicus (Norway rat)Dsg4NP_955784.1
Gallus gallus (chicken)DSG4XP_426082.4
Xenopus (Silurana) tropicalis (western clawed frog)dsg4XP_002934178.2
Process
IDNameEvidence
GO:0007156homophilic cell adhesionIEA
GO:0016337single organismal cell-cell adhesionIEA
GO:0030216keratinocyte differentiationIEA
GO:0030509BMP signaling pathwayIEA
GO:0042640anagenIEA
Component
IDNameEvidence
GO:0005886plasma membraneIEA
GO:0016021integral component of membraneIEA
GO:0030057desmosomeIEA
Function
IDNameEvidence
GO:0005509calcium ion bindingIEA
GeneCards DSG4
UniProt Q86SJ6
Vega OTTHUMG00000131979
MIM 607892
Ensembl ENSG00000175065
HGNC 21307
HPRD 06387

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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