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Sequence in raw or FASTA format:

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CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000782 Homo sapiens cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), nuclear gene encoding mitochondrial protein, transcript variant 1, mRNA. ORF Sequence $448.05
Peptide Services
Antibody Services
Protein Services
NM_001128915 Homo sapiens cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1), transcript variant 2, mRNA. ORF Sequence $390.63
Peptide Services
Antibody Services
Protein Services


Gene Symbol CYP24A1
Entrez Gene ID 1591
Full Name cytochrome P450, family 24, subfamily A, polypeptide 1
Synonyms CP24, CYP24, MGC126273, MGC126274, P450-CC24
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

20

20q13

Summary This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 126065

mRNA Protein Product Sequence Price Select
NM_000782, 193083115 NP_000773, 55770850 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform 1 precursor Full Length $1150.45
ORF Sequence $448.05
NM_001128915, 193083116 NP_001122387, 193083117 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial isoform 2 precursor Full Length $1081.15
ORF Sequence $390.63
KEGG
hsa00100Steroid biosynthesis
WikiPathways
WP1531Vitamin D synthesis
WP43cytochrome P450
WP299Nuclear receptors in lipid metabolism and toxicity
WP702metapathway biotransformation
Reactome
REACT_13433Biological oxidations
REACT_13567Cytochrome P450 - arranged by substrate type
REACT_111217Metabolism
REACT_11057Metabolism of steroid hormones and vitamins A and D
REACT_13523Vitamin D (calciferol) metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_13705Phase 1 - Functionalization of compounds
REACT_13450Vitamins
Homo sapiens (human)CYP24A1NP_000773.2
Pan troglodytes (chimpanzee)LOC746729XP_001154704.2
Macaca mulatta (Rhesus monkey)LOC698937XP_002798136.1
Canis lupus familiaris (dog)CYP24A1XP_543059.2
Bos taurus (cattle)CYP24A1NP_001178346.1
Mus musculus (house mouse)Cyp24a1NP_034126.1
Rattus norvegicus (Norway rat)Cyp24a1NP_963966.1
Gallus gallus (chicken)CYP24A1NP_990310.1
Danio rerio (zebrafish)cyp24a1NP_001082927.1
Drosophila melanogaster (fruit fly)Cyp12b2NP_611370.2
Caenorhabditis eleganscyp-44A1NP_495052.1
GeneCards CYP24A1
UniProt Q07973
MIM 126065
Ensembl ENSG00000019186
HGNC 2602
HPRD 00522

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
Names
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial
24-OHase
cytochrome P450 24A1
cytochrome P450-CC24
vitamin D 24-hydroxylase
exo-mitochondrial protein
vitamin D(3) 24-hydroxylase
1,25-@dihydroxyvitamin D3 24-hydroxylase
cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
NP_000773.2
NP_001122387.1

Interactant

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