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SPRED1 sprouty-related, EVH1 domain containing 1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_152594 Homo sapiens sprouty-related, EVH1 domain containing 1 (SPRED1), mRNA. GenEZ ORF Cloning On-demand $699.00 18

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Gene Symbol SPRED1
Entrez Gene ID 161742
Full Name sprouty-related, EVH1 domain containing 1
Synonyms FLJ33903, NFLS
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

15

15q14

Summary The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008].
Disorder

MIM: 609291

Legius syndrome, 611431 (3)

mRNA Protein Product Sequence Price Select
NM_152594, 187169267 NP_689807, 22749221 sprouty-related, EVH1 domain-containing protein 1 ORF Sequence $550.00
KEGG
hsa04630Jak-STAT signaling pathway
WikiPathways
WP304Kit Receptor Signaling Pathway
Pathway Interaction Database
kitpathwaySignaling events mediated by Stem cell factor receptor (c-Kit)
Homo sapiens (human)SPRED1NP_689807.1
Pan troglodytes (chimpanzee)SPRED1XP_001138171.1
Canis lupus familiaris (dog)SPRED1XP_544609.3
Bos taurus (cattle)SPRED1NP_001179445.1
Mus musculus (house mouse)Spred1NP_277059.1
Rattus norvegicus (Norway rat)Spred1NP_001040554.1
Gallus gallus (chicken)SPRED1NP_001186638.1
Danio rerio (zebrafish)spred1NP_998397.1
Drosophila melanogaster (fruit fly)SpredNP_610988.1
GeneCards SPRED1
PDB 3SYX
UniProt Q7Z699
MIM 609291
Ensembl ENSG00000166068
HGNC 20249
HPRD 11601

General protein information

Interactant



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