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DAZL deleted in azoospermia-like [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001190811 Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 1, mRNA. GenEZ ORF Cloning On-demand $449.00 14
NM_001351 Homo sapiens deleted in azoospermia-like (DAZL), transcript variant 2, mRNA. GenEZ ORF Cloning In-stock $348.00 $299.00 10

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Related Services

Gene Symbol DAZL
Entrez Gene ID 1618
Full Name deleted in azoospermia-like
Synonyms DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p24.3

Summary The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
Disorder

MIM: 601486

{Spermatogenic failure, susceptibility to} (3)

mRNA Protein Product Sequence Price Select
NM_001190811, 299829261 NP_001177740, 299829262 deleted in azoospermia-like isoform 1 ORF Sequence $300.00
NM_001351, 299829260 NP_001342, 25121978 deleted in azoospermia-like isoform 2 ORF Sequence $199.00
WikiPathways
WP34Ovarian Infertility Genes
Homo sapiens (human)DAZLNP_001342.2
Pan troglodytes (chimpanzee)DAZLXP_516314.3
Canis lupus familiaris (dog)DAZLXP_534251.3
Bos taurus (cattle)DAZLNP_001075194.1
Gallus gallus (chicken)DAZLNP_989549.1
Danio rerio (zebrafish)dazlNP_571599.1
GeneCards DAZL
UniProt Q92904
MIM 601486
Ensembl ENSG00000092345
HGNC 2685
HPRD 09029

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
deleted in azoospermia-like
Names
deleted in azoospermia-like
DAZ homolog
DAZ-like autosomal
SPGY-like-autosomal
deleted in azoospermia-like 1
germline specific RNA binding protein
spermatogenesis gene on the Y-like autosomal

Interactant



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