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Sequence in raw or FASTA format:


Blast Method:


DLX5 distal-less homeobox 5 [Homo sapiens (human)]

Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18344 NM_005221 Homo sapiens distal-less homeobox 5 (DLX5), mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu41401 XM_005250185 PREDICTED: Homo sapiens distal-less homeobox 5 (DLX5), transcript variant X1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu18344C NM_005221 Homo sapiens distal-less homeobox 5 (DLX5), mRNA. Customized vector In-stock 5-7 $149.00
OHu41401C XM_005250185 PREDICTED: Homo sapiens distal-less homeobox 5 (DLX5), transcript variant X1, mRNA. Customized vector In-stock 5-7 $149.00

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Gene Symbol DLX5
Entrez Gene ID 1749
Full Name distal-less homeobox 5
Synonyms SHFM1D
General protein information
Preferred Names
homeobox protein DLX-5
homeobox protein DLX-5
distal-less homeo box 5
split hand/foot malformation type 1 with sensorineural hearing loss
Gene Type protein-coding
Organism Homo sapiens (human)



Summary This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation. [provided by RefSeq, Jul 2008].

MIM: 600028

mRNA Protein Product Sequence Price Select
NM_005221, 84043959 NP_005212, 4885187 homeobox protein DLX-5 ORF Sequence $199.00
XM_005250185, 530385568 XP_005250242, 530385569 homeobox protein DLX-5 isoform X1 ORF Sequence $250.00
WP2064Neural Crest Differentiation
Homo sapiens (human)DLX5NP_005212.1
Pan troglodytes (chimpanzee)DLX5XP_519218.2
Macaca mulatta (Rhesus monkey)DLX5XP_001090332.1
Canis lupus familiaris (dog)DLX5XP_850412.1
Bos taurus (cattle)DLX5NP_001068781.1
Mus musculus (house mouse)Dlx5NP_034186.2
Rattus norvegicus (Norway rat)Dlx5NP_037075.1
Gallus gallus (chicken)DLX5NP_989490.1
Danio rerio (zebrafish)dlx5aNP_571381.1
Xenopus (Silurana) tropicalis (western clawed frog)dlx5NP_001004778.1
GO:0001501skeletal system developmentTAS
GO:0001649osteoblast differentiationISS
GO:0001958endochondral ossificationISS
GO:0006351transcription, DNA-templatedIEA
GO:0007399nervous system developmentTAS
GO:0007411axon guidanceIEA
GO:0008283cell proliferationIDA
GO:0030326embryonic limb morphogenesisIEA
GO:0030509BMP signaling pathwayISS
GO:0030855epithelial cell differentiationIEA
GO:0042472inner ear morphogenesisIEA
GO:0045669positive regulation of osteoblast differentiationIEA
GO:0045893positive regulation of transcription, DNA-templatedIDA
GO:0048646anatomical structure formation involved in morphogenesisIEA
GO:0050679positive regulation of epithelial cell proliferationIEA
GO:0060021palate developmentIEA
GO:0060166olfactory pit developmentIEA
GO:0060325face morphogenesisIEA
GO:0071773cellular response to BMP stimulusISS
GO:0090263positive regulation of canonical Wnt signaling pathwayIEA
GO:1901522positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulusISS
GO:0000790nuclear chromatinISS
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA bindingISS
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionISS
GO:0044212transcription regulatory region DNA bindingIDA
GO:0071837HMG box domain bindingIEA
GeneCards DLX5
UniProt Q53Y73, P56178
Vega OTTHUMG00000154200
MIM 600028
Ensembl ENSG00000105880
HGNC 2918
HPRD 02492

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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