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DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001376 Homo sapiens dynein, cytoplasmic 1, heavy chain 1 (DYNC1H1), mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services


Gene Symbol DYNC1H1
Entrez Gene ID 1778
Full Name dynein, cytoplasmic 1, heavy chain 1
Synonyms DHC1, DHC1a, DKFZp686P2245, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, KIAA0325, p22
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q32.3-qter|14q32

Summary Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008].
Disorder

MIM: 600112

mRNA Protein Product Sequence Price Select
NM_001376, 209413718 NP_001367, 33350932 cytoplasmic dynein 1 heavy chain 1 Full Length $0.00
ORF Sequence $0.00
KEGG
hsa04145Phagosome
hsa05132Salmonella infection
hsa04962Vasopressin-regulated water reabsorption
Pathway Interaction Database
lis1pathwayLissencephaly gene (LIS1) in neuronal migration and development
Reactome
REACT_152Cell Cycle, Mitotic
REACT_15451Loss of proteins required for interphase microtubule organization####from the centrosome
REACT_15479Centrosome maturation
REACT_15296Recruitment of mitotic centrosome proteins and complexes
REACT_21391Mitotic G2-G2/M phases
REACT_75774Adaptive Immune System
REACT_115566Cell Cycle
REACT_121399MHC class II antigen presentation
REACT_2203G2/M Transition
REACT_6900Immune System
REACT_15364Loss of Nlp from mitotic centrosomes
Homo sapiens (human)DYNC1H1NP_001367.2
Pan troglodytes (chimpanzee)DYNC1H1XP_003314564.1
Macaca mulatta (Rhesus monkey)LOC718989XP_001112455.2
Canis lupus familiaris (dog)DYNC1H1XP_537556.2
Bos taurus (cattle)DYNC1H1NP_001193067.1
Mus musculus (house mouse)Dync1h1NP_084514.2
Rattus norvegicus (Norway rat)Dync1h1NP_062099.3
Gallus gallus (chicken)DYNC1H1XP_421371.3
Danio rerio (zebrafish)dync1h1NP_001036210.1
Drosophila melanogaster (fruit fly)Dhc64CNP_729034.2
Caenorhabditis elegansdhc-1NP_491363.1
GeneCards DYNC1H1
PDB 2BOR, 2BOT
UniProt Q14204
MIM 600112
Ensembl ENSG00000197102
HGNC 2961
HPRD 02524

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
cytoplasmic dynein 1 heavy chain 1
Names
cytoplasmic dynein 1 heavy chain 1
dynein heavy chain, cytosolic
dynein, cytoplasmic, heavy polypeptide 1

Interactant

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