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DRD1 dopamine receptor D1 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000794 Homo sapiens dopamine receptor D1 (DRD1), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Related Services

Gene Symbol DRD1
Entrez Gene ID 1812
Full Name dopamine receptor D1
Synonyms DADR, DRD1A
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

5

5q35.1

Summary This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 126449

mRNA Protein Product Sequence Price Select
NM_000794, 88758587 NP_000785, 4503383 D(1A) dopamine receptor ORF Sequence $360.00
KEGG
hsa05034Alcoholism
hsa05032Morphine addiction
hsa04080Neuroactive ligand-receptor interaction
hsa04020Calcium signaling pathway
hsa05031Amphetamine addiction
hsa04540Gap junction
hsa05030Cocaine addiction
hsa04728Dopaminergic synapse
WikiPathways
WP455GPCRs, Class A Rhodopsin-like
WP58Monoamine GPCRs
WP666Hypothetical Network for Drug Addiction
Reactome
REACT_16983Amine ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_19327G alpha (s) signalling events
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_16968Dopamine receptors
REACT_21340GPCR ligand binding
REACT_19184GPCR downstream signaling
Homo sapiens (human)DRD1NP_000785.1
Pan troglodytes (chimpanzee)DRD1XP_001149473.2
Canis lupus familiaris (dog)DRD1XP_546227.2
Bos taurus (cattle)DRD1NP_776467.1
Mus musculus (house mouse)Drd1aNP_034206.1
Rattus norvegicus (Norway rat)Drd1aNP_036678.2
Gallus gallus (chicken)DRD1NP_001138320.1
Danio rerio (zebrafish)drd1NP_001129448.1
Drosophila melanogaster (fruit fly)DopRNP_477007.2
GeneCards DRD1
PDB 1OZ5
UniProt P21728
MIM 126449
Ensembl ENSG00000184845
HGNC 3020
HPRD 00538

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
D(1A) dopamine receptor
Names
D(1A) dopamine receptor
dopamine D1 receptor

Interactant



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