• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


DRD4 dopamine receptor D4 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000797 Homo sapiens dopamine receptor D4 (DRD4), mRNA. GenEZ ORF Cloning On-demand TBD TBD

*Business Day

Related Services

Gene Symbol DRD4
Entrez Gene ID 1815
Full Name dopamine receptor D4
Synonyms D4DR
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11p15.5

Summary This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008].
Disorder

MIM: 126452

Autonomic nervous system dysfunction (3); [Novelty seeking

mRNA Protein Product Sequence Price Select
NM_000797, 296010830 NP_000788, 32483397 D(4) dopamine receptor ORF Sequence $550.00
KEGG
hsa04080Neuroactive ligand-receptor interaction
hsa04728Dopaminergic synapse
WikiPathways
WP58Monoamine GPCRs
WP455GPCRs, Class A Rhodopsin-like
WP1602Nicotine Activity on Dopaminergic Neurons
WP117GPCRs, Other
WP666Hypothetical Network for Drug Addiction
Reactome
REACT_16983Amine ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_16968Dopamine receptors
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
Homo sapiens (human)DRD4NP_000788.2
Pan troglodytes (chimpanzee)DRD4XP_001149749.1
Macaca mulatta (Rhesus monkey)DRD4XP_001087197.1
Mus musculus (house mouse)Drd4NP_031904.1
Rattus norvegicus (Norway rat)Drd4NP_037076.1
Gallus gallus (chicken)DRD4NP_001136321.1
Danio rerio (zebrafish)drd4aNP_001012634.1
Danio rerio (zebrafish)drd4bNP_001012636.1
GeneCards DRD4
UniProt P21917
MIM 126452
Ensembl ENSG00000069696
HGNC 3025
HPRD 00541

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
D(4) dopamine receptor
Names
D(4) dopamine receptor
dopamine D4 receptor
D(2C) dopamine receptor
seven transmembrane helix receptor

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.