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DRD5 dopamine receptor D5 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000798 Homo sapiens dopamine receptor D5 (DRD5), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

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Gene Symbol DRD5
Entrez Gene ID 1816
Full Name dopamine receptor D5
Synonyms DBDR, DRD1B, DRD1L2, MGC10601
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4p16.1

Summary This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008].
Disorder

MIM: 126453

{Blepharospasm, primary benign}, 606798 (3); Dystonia, primary

mRNA Protein Product Sequence Price Select
NM_000798, 171919773 NP_000789, 4503391 D(1B) dopamine receptor ORF Sequence $360.00
KEGG
hsa04020Calcium signaling pathway
hsa04728Dopaminergic synapse
hsa04080Neuroactive ligand-receptor interaction
WikiPathways
WP58Monoamine GPCRs
WP455GPCRs, Class A Rhodopsin-like
Reactome
REACT_19184GPCR downstream signaling
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_16983Amine ligand-binding receptors
REACT_16968Dopamine receptors
REACT_21340GPCR ligand binding
REACT_111102Signal Transduction
REACT_19327G alpha (s) signalling events
REACT_14797Signaling by GPCR
Homo sapiens (human)DRD5NP_000789.1
Pan troglodytes (chimpanzee)DRD5XP_528711.2
Macaca mulatta (Rhesus monkey)DRD5XP_001097117.1
Canis lupus familiaris (dog)DRD5XP_545942.3
Bos taurus (cattle)DRD5NP_001193558.1
Mus musculus (house mouse)Drd5NP_038531.1
Rattus norvegicus (Norway rat)Drd5NP_036900.1
Gallus gallus (chicken)DRD5XP_426351.3
Danio rerio (zebrafish)LOC563567XP_692025.3
Danio rerio (zebrafish)LOC100001636XP_001341592.2
GeneCards DRD5
UniProt P21918
MIM 126453
Ensembl ENSG00000169676
HGNC 3026
HPRD 00542

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
D(1B) dopamine receptor
Names
D(1B) dopamine receptor
dopamine D5 receptor
dopamine receptor D1B
d(5) dopamine receptor
D1beta dopamine receptor

Interactant



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