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Sequence in raw or FASTA format:

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TYMP thymidine phosphorylase [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001113755 Homo sapiens thymidine phosphorylase (TYMP), transcript variant 1, mRNA. ORF Sequence $420.21
Peptide Services
Antibody Services
Protein Services
NM_001113756 Homo sapiens thymidine phosphorylase (TYMP), transcript variant 3, mRNA. ORF Sequence $420.21
Peptide Services
Antibody Services
Protein Services
NM_001257988 Homo sapiens thymidine phosphorylase (TYMP), transcript variant 4, mRNA. ORF Sequence $420.21
Peptide Services
Antibody Services
Protein Services
NM_001257989 Homo sapiens thymidine phosphorylase (TYMP), nuclear gene encoding mitochondrial protein, transcript variant 5, mRNA. ORF Sequence $424.56
Peptide Services
Antibody Services
Protein Services
NM_001953 Homo sapiens thymidine phosphorylase (TYMP), transcript variant 2, mRNA. ORF Sequence $420.21
Peptide Services
Antibody Services
Protein Services


Gene Symbol TYMP
Entrez Gene ID 1890
Full Name thymidine phosphorylase
Synonyms ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

22

22q13|22q13.33

Summary This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012].
Disorder

MIM: 131222

Mitochondrial DNA depletion syndrome 1 (MNGIE type), 603041 (3)

mRNA Protein Product Sequence Price Select
NM_001113755, 384229045 NP_001107227, 166158922 thymidine phosphorylase isoform 1 proprotein Full Length $486.91
ORF Sequence $420.21
NM_001113756, 384229047 NP_001107228, 166158925 thymidine phosphorylase isoform 1 proprotein Full Length $536.79
ORF Sequence $420.21
NM_001257988, 384229048 NP_001244917, 384229049 thymidine phosphorylase isoform 1 proprotein Full Length $498.22
ORF Sequence $420.21
NM_001257989, 384229050 NP_001244918, 384229051 thymidine phosphorylase isoform 2 proprotein Full Length $487.78
ORF Sequence $424.56
NM_001953, 384229046 NP_001944, 4503445 thymidine phosphorylase isoform 1 proprotein Full Length $483.43
ORF Sequence $420.21
KEGG
hsa00240Pyrimidine metabolism
hsa05219Bladder cancer
hsa00983Drug metabolism - other enzymes
WikiPathways
WP1601Fluoropyrimidine Activity
BIOCYC
HUMAN_PWY0-181salvage pathways of pyrimidine deoxyribonucleotides
Reactome
REACT_111217Metabolism
REACT_655Pyrimidine salvage reactions
REACT_1023Pyrimidine catabolism
REACT_1698Metabolism of nucleotides
REACT_957Pyrimidine metabolism
Homo sapiens (human)TYMPNP_001107227.1
Pan troglodytes (chimpanzee)TYMPXP_515224.4
Macaca mulatta (Rhesus monkey)TYMPXP_001112886.1
Mus musculus (house mouse)TympNP_612175.1
Rattus norvegicus (Norway rat)TympNP_001012122.1
GeneCards TYMP
PDB 2WK6, 2J0F, 2WK5, 1UOU
UniProt E5KRG5, B2RBL3, P19971
MIM 131222
Ensembl ENSG00000025708
HGNC 3148
HPRD 08833

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
thymidine phosphorylase
Names
thymidine phosphorylase
tdRPase
gliostatin
NP_001107227.1
NP_001107228.1
NP_001244917.1
NP_001244918.1
NP_001944.1

Interactant

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