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Sequence in raw or FASTA format:

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ELAVL1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001419 Homo sapiens ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (ELAVL1), mRNA. ORF Sequence $284.49
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Gene Symbol ELAVL1
Entrez Gene ID 1994
Full Name ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
Synonyms ELAV1, HUR, Hua, MelG
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.2

Summary The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012].
Disorder

MIM: 603466

mRNA Protein Product Sequence Price Select
NM_001419, 38201713 NP_001410, 38201714 ELAV-like protein 1 Full Length $2733.75
ORF Sequence $284.49
WikiPathways
WP1403AMPK signaling
Reactome
REACT_71Gene Expression
REACT_24994Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
REACT_25218Stabilization of mRNA by HuR
Homo sapiens (human)ELAVL1NP_001410.2
Pan troglodytes (chimpanzee)ELAVL1XP_001156587.2
Macaca mulatta (Rhesus monkey)ELAVL1XP_001092907.2
Canis lupus familiaris (dog)ELAVL1XP_854218.1
Bos taurus (cattle)ELAVL1NP_001069922.1
Mus musculus (house mouse)Elavl1NP_034615.2
Rattus norvegicus (Norway rat)Elavl1NP_001102318.1
Gallus gallus (chicken)ELAVL1NP_990164.1
Danio rerio (zebrafish)hugNP_570984.1
Caenorhabditis elegansexc-7NP_496057.1
GeneCards ELAVL1
PDB 4EGL, 4ED5, 4FXV, 3HI9
UniProt Q15717
MIM 603466
Ensembl ENSG00000066044
HGNC 3312
HPRD 16025

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ELAV-like protein 1
Names
ELAV-like protein 1
Hu antigen R
hu-antigen R
embryonic lethal, abnormal vision, drosophila, homolog-like 1

Interactant

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