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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


EPHA3 EPH receptor A3 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu15678 NM_182644 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu19238 NM_005233 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu37037 XM_005264715 PREDICTED: Homo sapiens EPH receptor A3 (EPHA3), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu37038 XM_005264716 PREDICTED: Homo sapiens EPH receptor A3 (EPHA3), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu15678C NM_182644 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 2, mRNA. Customized vector On-demand 7-9 $269.00
OHu19238C NM_005233 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA. Customized vector On-demand 12-14 $329.00
OHu37037C XM_005264715 PREDICTED: Homo sapiens EPH receptor A3 (EPHA3), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu37038C XM_005264716 PREDICTED: Homo sapiens EPH receptor A3 (EPHA3), transcript variant X2, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol EPHA3
Entrez Gene ID 2042
Full Name EPH receptor A3
Synonyms EK4, ETK, ETK1, HEK, HEK4, TYRO4
General protein information
Preferred Names
ephrin type-A receptor 3
Names
ephrin type-A receptor 3
EPH-like kinase 4
human embryo kinase 1
eph-like tyrosine kinase 1
TYRO4 protein tyrosine kinase
tyrosine-protein kinase receptor ETK1
NP_005224.2
NP_872585.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p11.2

Summary This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 179611

mRNA Protein Product Sequence Price Select
NM_005233, 156547090 NP_005224, 21361241 ephrin type-A receptor 3 isoform a precursor ORF Sequence $750.00
NM_182644, 156547125 NP_872585, 32967314 ephrin type-A receptor 3 isoform b precursor ORF Sequence $550.00
XM_005264715, 530373624 XP_005264772, 530373625 ephrin type-A receptor 3 isoform X1 ORF Sequence $750.00
XM_005264716, 530373626 XP_005264773, 530373627 ephrin type-A receptor 3 isoform X2 ORF Sequence $750.00
KEGG
hsa04360Axon guidance
Pathway Interaction Database
ephrina_ephapathwayEphrinA-EPHA pathway
epha_fwdpathwayEPHA forward signaling
Homo sapiens (human)EPHA3NP_005224.2
Pan troglodytes (chimpanzee)EPHA3XP_516601.2
Macaca mulatta (Rhesus monkey)EPHA3XP_001083136.1
Canis lupus familiaris (dog)EPHA3XP_005639499.1
Bos taurus (cattle)EPHA3NP_001193042.1
Mus musculus (house mouse)Epha3NP_034270.1
Rattus norvegicus (Norway rat)Epha3NP_113752.1
Gallus gallus (chicken)EPHA3NP_990761.1
Xenopus (Silurana) tropicalis (western clawed frog)epha3XP_002931819.1
Process
IDNameEvidence
GO:0007155cell adhesionIEA
GO:0010717regulation of epithelial to mesenchymal transitionISS
GO:0010976positive regulation of neuron projection developmentIMP
GO:0016477cell migrationISS
GO:0018108peptidyl-tyrosine phosphorylationIEA
GO:0032319regulation of Rho GTPase activityIDA
GO:0032956regulation of actin cytoskeleton organizationIDA
GO:0048013ephrin receptor signaling pathwayIDA
GO:0051893regulation of focal adhesion assemblyIDA
GO:0070507regulation of microtubule cytoskeleton organizationIDA
GO:0071300cellular response to retinoic acidIMP
GO:0097155fasciculation of sensory neuron axonISS
GO:0097156fasciculation of motor neuron axonISS
Component
IDNameEvidence
GO:0005576extracellular regionIEA
GO:0005769early endosomeIDA
GO:0005887integral component of plasma membraneIDA
Function
IDNameEvidence
GO:0005004GPI-linked ephrin receptor activityIDA
GO:0005515protein bindingIPI
GO:0005524ATP bindingIEA
GeneCards EPHA3
UniProt P29320, C9JXA2, Q6P4R6
Vega OTTHUMG00000159040
MIM 179611
Ensembl ENSG00000044524
HGNC 3387
HPRD 01555

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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