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Sequence in raw or FASTA format:

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EPHA3 EPH receptor A3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_005233 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 1, mRNA. ORF Sequence $856.08
Peptide Services
Antibody Services
Protein Services
NM_182644 Homo sapiens EPH receptor A3 (EPHA3), transcript variant 2, mRNA. ORF Sequence $469.80
Peptide Services
Antibody Services
Protein Services


Gene Symbol EPHA3
Entrez Gene ID 2042
Full Name EPH receptor A3
Synonyms EK4, ETK, ETK1, HEK, HEK4, TYRO4
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

3

3p11.2

Summary This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 179611

mRNA Protein Product Sequence Price Select
NM_005233, 156547090 NP_005224, 21361241 ephrin type-A receptor 3 isoform a precursor Full Length $2626.65
ORF Sequence $856.08
NM_182644, 156547125 NP_872585, 32967314 ephrin type-A receptor 3 isoform b precursor Full Length $778.36
ORF Sequence $469.80
KEGG
hsa04360Axon guidance
Pathway Interaction Database
ephrina_ephapathwayEphrinA-EPHA pathway
epha_fwdpathwayEPHA forward signaling
Homo sapiens (human)EPHA3NP_005224.2
Pan troglodytes (chimpanzee)EPHA3XP_516601.2
Macaca mulatta (Rhesus monkey)EPHA3XP_001083136.1
Canis lupus familiaris (dog)EPHA3XP_545052.3
Bos taurus (cattle)EPHA3NP_001193042.1
Mus musculus (house mouse)Epha3NP_034270.1
Rattus norvegicus (Norway rat)Epha3NP_113752.1
Gallus gallus (chicken)EPHA3NP_990761.1
GeneCards EPHA3
PDB 2QO9, 2QOL, 2QON, 3DZQ, 2QOI, 4GK3, 2QOF, 2QO2, 3FXX, 4G2F, 3FY2, 2QOK, 4GK2, 2QOB, 2QOQ, 2QOD, 2GSF, 2QOO, 4GK4, 2QOC, 2QO7
UniProt P29320, Q6P4R6
MIM 179611
Ensembl ENSG00000044524
HGNC 3387
HPRD 01555

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ephrin type-A receptor 3
Names
ephrin type-A receptor 3
EPH-like kinase 4
human embryo kinase 1
eph-like tyrosine kinase 1
TYRO4 protein tyrosine kinase
tyrosine-protein kinase receptor ETK1
NP_005224.2
NP_872585.1

Interactant

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