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EPHA5 EPH receptor A5 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu00707 NM_001281767 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 5, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu01240 NM_001281765 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu01742 NM_004439 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu10633 NM_182472 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 2, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu11585 NM_001281766 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand TBD TBD
OHu38772 XM_005265653 PREDICTED: Homo sapiens EPH receptor A5 (EPHA5), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu00707C NM_001281767 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 5, mRNA. Customized vector On-demand TBD TBD
OHu01240C NM_001281765 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 3, mRNA. Customized vector On-demand TBD TBD
OHu01742C NM_004439 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 1, mRNA. Customized vector On-demand TBD TBD
OHu10633C NM_182472 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 2, mRNA. Customized vector On-demand TBD TBD
OHu11585C NM_001281766 Homo sapiens EPH receptor A5 (EPHA5), transcript variant 4, mRNA. Customized vector On-demand TBD TBD
OHu38772C XM_005265653 PREDICTED: Homo sapiens EPH receptor A5 (EPHA5), transcript variant X4, mRNA. Customized vector On-demand 12-14 $329.00

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Gene Symbol EPHA5
Entrez Gene ID 2044
Full Name EPH receptor A5
Synonyms CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4
General protein information
Preferred Names
ephrin type-A receptor 5
Names
ephrin type-A receptor 5
EK7
EHK-1
EPH-like kinase 7
EPH homology kinase 1
Eph homology kinase-1
brain-specific kinase
receptor protein-tyrosine kinase HEK7
tyrosine-protein kinase receptor EHK-1
NP_004430.4
NP_872272.2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q13.1

Summary This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Aug 2013].
Disorder

MIM: 600004

mRNA Protein Product Sequence Price Select
NM_001281765, 528881088 NP_001268694, 528881089 ephrin type-A receptor 5 isoform c ORF Sequence $1500.00
NM_001281766, 528881273 NP_001268695, 528881274 ephrin type-A receptor 5 isoform d ORF Sequence $1500.00
NM_001281767, 528881090 NP_001268696, 528881091 ephrin type-A receptor 5 isoform e ORF Sequence $1500.00
NM_004439, 528881086 NP_004430, 221625401 ephrin type-A receptor 5 isoform a ORF Sequence $1500.00
NM_182472, 528881087 NP_872272, 221625422 ephrin type-A receptor 5 isoform b ORF Sequence $1500.00
XM_005265653, 530376906 XP_005265710, 530376907 ephrin type-A receptor 5 isoform X4 ORF Sequence $750.00
KEGG
hsa04360Axon guidance
Pathway Interaction Database
ephrina_ephapathwayEphrinA-EPHA pathway
ephrinarevpathwayEphrin A reverse signaling
epha_fwdpathwayEPHA forward signaling
Homo sapiens (human)EPHA5NP_001268694.1
Pan troglodytes (chimpanzee)EPHA5XP_001165182.1
Macaca mulatta (Rhesus monkey)EPHA5XP_001109851.2
Canis lupus familiaris (dog)EPHA5XP_005628299.1
Bos taurus (cattle)LOC100337226XP_005208108.1
Mus musculus (house mouse)Epha5NP_031963.2
Rattus norvegicus (Norway rat)Epha5NP_001162608.1
Gallus gallus (chicken)EPHA5NP_990436.2
Danio rerio (zebrafish)LOC797595XP_001338064.4
Xenopus (Silurana) tropicalis (western clawed frog)epha5XP_002936506.2
Process
IDNameEvidence
GO:0007411axon guidanceISS
GO:0018108peptidyl-tyrosine phosphorylationIEA
GO:0019933cAMP-mediated signalingISS
GO:0021766hippocampus developmentISS
GO:0032314regulation of Rac GTPase activityISS
GO:0032793positive regulation of CREB transcription factor activityISS
GO:0032956regulation of actin cytoskeleton organizationISS
GO:0048013ephrin receptor signaling pathwayISS
GO:0048666neuron developmentIEP
GO:0051964negative regulation of synapse assemblyIEA
GO:0061178regulation of insulin secretion involved in cellular response to glucose stimulusISS
Component
IDNameEvidence
GO:0005791rough endoplasmic reticulumIDA
GO:0005886plasma membraneIDA
GO:0005887integral component of plasma membraneIEA
GO:0009897external side of plasma membraneIDA
GO:0030424axonIEA
GO:0030425dendriteIDA
GO:0043025neuronal cell bodyIDA
GO:0048471perinuclear region of cytoplasmIDA
Function
IDNameEvidence
GO:0005003ephrin receptor activityISS
GO:0005004GPI-linked ephrin receptor activityISS
GO:0005005transmembrane-ephrin receptor activityNAS
GO:0005524ATP bindingIEA
GeneCards EPHA5
UniProt B7ZKW7, P54756, Q59FT4, B7ZKJ3, F8W9W0, F8VP57
Vega OTTHUMG00000129273
MIM 600004
Ensembl ENSG00000145242
HGNC 3389
HPRD 02474

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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