• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


EPOR erythropoietin receptor [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000121 Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12

*Business Day

Related Services

Gene Symbol EPOR
Entrez Gene ID 2057
Full Name erythropoietin receptor
Synonyms EPO-R, MGC138358
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

19

19p13.3-p13.2

Summary This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].
Disorder

MIM: 133171

[Erythrocytosis, familial], 133100 (3)

mRNA Protein Product Sequence Price Select
NM_000121, 296040523 NP_000112, 4503591 erythropoietin receptor precursor ORF Sequence $360.00
KEGG
hsa04151PI3K-Akt signaling pathway
hsa04630Jak-STAT signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa04640Hematopoietic cell lineage
WikiPathways
WP581EPO Receptor Signaling
WP304Kit Receptor Signaling Pathway
Pathway Interaction Database
kitpathwaySignaling events mediated by Stem cell factor receptor (c-Kit)
a4b1_paxindep_pathwayPaxillin-independent events mediated by a4b1 and a4b7
epopathwayEPO signaling pathway
Homo sapiens (human)EPORNP_000112.1
Macaca mulatta (Rhesus monkey)EPORXP_001105833.1
Canis lupus familiaris (dog)EPORNP_001041576.1
Bos taurus (cattle)EPORNP_001192530.1
Mus musculus (house mouse)EporNP_034279.3
Rattus norvegicus (Norway rat)EporNP_058698.2
Danio rerio (zebrafish)eporNP_001036799.1
Danio rerio (zebrafish)LOC100534667XP_003198123.1
GeneCards EPOR
PDB 2JIX, 1EBP, 1EBA, 1CN4, 1ERN, 1EER
UniProt P19235
MIM 133171
Ensembl ENSG00000187266
HGNC 3416
HPRD 00587

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
erythropoietin receptor
Names
erythropoietin receptor

Interactant



Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.

Learn more about the GenEZ ORF Cloning Service.