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ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_000122 Homo sapiens excision repair cross-complementing rodent repair deficiency, complementation group 3 (ERCC3), mRNA. GenEZ ORF Cloning On-demand $899.00 20

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Related Services

Gene Symbol ERCC3
Entrez Gene ID 2071
Full Name excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)
Synonyms BTF2, GTF2H, RAD25, TFIIH, XPB
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2q21

Summary ERCC3 is an ATP-dependent DNA helicase that functions in nucleotide excision repair and complements xeroderma pigmentosum group B mutations. It also is the 89 kDa subunit of basal transcription factor 2 (TFIIH) and thus functions in class II transcription. [provided by RefSeq, Jul 2008].
Disorder

MIM: 133510

Xeroderma pigmentosum, group B, 610651 (3); Trichothiodystrophy,

mRNA Protein Product Sequence Price Select
NM_000122, 4557562 NP_000113, 4557563 TFIIH basal transcription factor complex helicase XPB subunit ORF Sequence $750.00
KEGG
hsa03420Nucleotide excision repair
hsa_M00290Holo-TFIIH complex
hsa03022Basal transcription factors
WikiPathways
WP405Eukaryotic Transcription Initiation
Reactome
REACT_216DNA Repair
REACT_311Dual incision reaction in GG-NER
REACT_2222Dual incision reaction in TC-NER
REACT_1074RNA Polymerase I Transcription Termination
REACT_21352RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
REACT_846Formation of the Early Elongation Complex
REACT_6162Tat-mediated elongation of the HIV-1 transcript
REACT_833RNA Polymerase II Transcription Elongation
REACT_2089RNA Polymerase II Promoter Escape
REACT_71Gene Expression
REACT_6274HIV-1 Transcription Elongation
REACT_6233Transcription of the HIV genome
REACT_257Formation of incision complex in GG-NER
REACT_6332HIV-1 Transcription Initiation
REACT_975RNA Pol II CTD phosphorylation and interaction with CE
REACT_22107RNA Polymerase II Pre-transcription Events
REACT_6346Formation of HIV-1 elongation complex containing HIV-1 Tat
REACT_1470mRNA Capping
REACT_2204RNA Polymerase I Chain Elongation
REACT_1974RNA Polymerase I Promoter Clearance
REACT_6361Late Phase of HIV Life Cycle
REACT_1366RNA Polymerase II Transcription
REACT_953RNA Polymerase I Transcription Initiation
REACT_6185HIV Infection
REACT_1628Transcription-coupled NER (TC-NER)
REACT_1826Nucleotide Excision Repair
REACT_6253RNA Polymerase II HIV-1 Promoter Escape
REACT_834RNA Polymerase II Transcription Initiation And Promoter Clearance
REACT_116125Disease
REACT_1913RNA Polymerase I Promoter Escape
REACT_6256HIV Life Cycle
REACT_1941Formation of transcription-coupled NER (TC-NER) repair complex
REACT_2253Global Genomic NER (GG-NER)
REACT_1655RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
REACT_1845Formation of RNA Pol II elongation complex
REACT_6237RNA Pol II CTD phosphorylation and interaction with CE
REACT_1851RNA Polymerase II Transcription Initiation
REACT_6319Formation of the HIV-1 Early Elongation Complex
REACT_22201Formation of HIV-1 elongation complex in the absence of HIV-1 Tat
REACT_1309RNA Polymerase I Transcription
Homo sapiens (human)ERCC3NP_000113.1
Pan troglodytes (chimpanzee)ERCC3XP_525907.3
Macaca mulatta (Rhesus monkey)ERCC3XP_001086722.1
Canis lupus familiaris (dog)ERCC3XP_533314.2
Bos taurus (cattle)ERCC3NP_001039453.1
Mus musculus (house mouse)Ercc3NP_598419.1
Rattus norvegicus (Norway rat)Ercc3NP_001026814.1
Gallus gallus (chicken)ERCC3NP_001006523.1
Danio rerio (zebrafish)ercc3NP_963876.1
Drosophila melanogaster (fruit fly)hayNP_001137931.1
Caenorhabditis elegansY66D12A.15NP_499487.1
Arabidopsis thaliana (thale cress)XPB2NP_568591.1
Arabidopsis thaliana (thale cress)XPB1NP_568592.1
GeneCards ERCC3
PDB 4ERN
UniProt P19447
MIM 133510
Ensembl ENSG00000163161
HGNC 3435
HPRD 00593

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
TFIIH basal transcription factor complex helicase XPB subunit
Names
TFIIH basal transcription factor complex helicase XPB subunit
BTF2 p89
TFIIH p89
TFIIH 89 kDa subunit
DNA excision repair protein ERCC-3
DNA repair protein complementing XP-B cells
basic transcription factor 2 89 kDa subunit
xeroderma pigmentosum, complementation group B
xeroderma pigmentosum group B-complementing protein
TFIIH basal transcription factor complex 89 kDa subunit
NP_000113.1

Interactant



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