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ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001089 Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3), mRNA. ORF Sequence $2301.75
Peptide Services
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Gene Symbol ABCA3
Entrez Gene ID 21
Full Name ATP-binding cassette, sub-family A (ABC1), member 3
Synonyms ABC-C, ABC3, EST111653, LBM180, MGC166979, MGC72201, SMDP3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p13.3

Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008].
Disorder

MIM: 601615

Surfactant metabolism dysfunction, pulmonary, 3, 610921 (3)

mRNA Protein Product Sequence Price Select
NM_001089, 116734709 NP_001080, 116734710 ATP-binding cassette sub-family A member 3 Full Length $2980.35
ORF Sequence $2301.75
KEGG
hsa02010ABC transporters
Reactome
REACT_15518Transmembrane transport of small molecules
REACT_15480ABC-family proteins mediated transport
REACT_111158ABCA transporters in lipid homeostasis
Homo sapiens (human)ABCA3NP_001080.2
Pan troglodytes (chimpanzee)ABCA3XP_510744.2
Macaca mulatta (Rhesus monkey)ABCA3XP_001085237.2
Canis lupus familiaris (dog)ABCA3XP_537004.4
Bos taurus (cattle)ABCA3NP_001107218.1
Mus musculus (house mouse)Abca3NP_038883.2
Rattus norvegicus (Norway rat)Abca3XP_220219.5
Gallus gallus (chicken)ABCA3XP_414701.3
Danio rerio (zebrafish)abca3XP_002661144.2
Drosophila melanogaster (fruit fly)CG1718NP_608445.2
Caenorhabditis elegansabt-4NP_503175.1
GeneCards ABCA3
UniProt Q99758, Q6P5P9, Q4LE27
MIM 601615
Ensembl ENSG00000167972
HGNC 33
HPRD 03369

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
ATP-binding cassette sub-family A member 3
Names
ATP-binding cassette sub-family A member 3
ABC transporter 3
ABC-C transporter
ATP-binding cassette transporter 3

Interactant

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