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Sequence in raw or FASTA format:

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ETV6 ets variant 6 [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001987 Homo sapiens ets variant 6 (ETV6), mRNA. ORF Sequence $394.11
Peptide Services
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Gene Symbol ETV6
Entrez Gene ID 2120
Full Name ets variant 6
Synonyms TEL, TEL/ABL
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

12

12p13

Summary This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008].
Disorder

MIM: 600618

Leukemia, acute myeloid, somatic, 601626 (3)

mRNA Protein Product Sequence Price Select
NM_001987, 153267458 NP_001978, 4503611 transcription factor ETV6 Full Length $2695.05
ORF Sequence $394.11
KEGG
hsa05202Transcriptional misregulation in cancer
hsa04320Dorso-ventral axis formation
WikiPathways
WP410Diurnally regulated genes with circadian orthologs
Homo sapiens (human)ETV6NP_001978.1
Pan troglodytes (chimpanzee)ETV6XP_528737.2
Macaca mulatta (Rhesus monkey)ETV6XP_001083583.1
Canis lupus familiaris (dog)ETV6XP_543812.3
Bos taurus (cattle)ETV6NP_001015514.2
Mus musculus (house mouse)Etv6NP_031987.3
Rattus norvegicus (Norway rat)Etv6NP_001032430.1
Gallus gallus (chicken)ETV6NP_001186202.1
Danio rerio (zebrafish)etv6NP_571907.2
GeneCards ETV6
PDB 2QB0, 2QAR, 1LKY, 1JI7, 2DAO, 2QB1
UniProt P41212
MIM 600618
Ensembl ENSG00000139083
HGNC 3495
HPRD 15976

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
transcription factor ETV6
Names
transcription factor ETV6
TEL1 oncogene
ETS-related protein Tel1
ETS translocation variant 6
ets variant gene 6 (TEL oncogene)

Interactant

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