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ALB albumin [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu18744 NM_000477 Homo sapiens albumin (ALB), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu18744C NM_000477 Homo sapiens albumin (ALB), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol ALB
Entrez Gene ID 213
Full Name albumin
Synonyms PRO0883, PRO0903, PRO1341
General protein information
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q13.3

Summary Albumin is a soluble, monomeric protein which comprises about one-half of the blood serum protein. Albumin functions primarily as a carrier protein for steroids, fatty acids, and thyroid hormones and plays a role in stabilizing extracellular fluid volume. Albumin is a globular unglycosylated serum protein of molecular weight 65,000. Albumin is synthesized in the liver as preproalbumin which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin. [provided by RefSeq, Jul 2008].
Disorder

MIM: 103600

Analbuminemia (3); [Dysalbuminemic hyperthyroxinemia] (3);

mRNA Protein Product Sequence Price Select
NM_000477, 215982788 NP_000468, 4502027 serum albumin preproprotein ORF Sequence $700.00
WikiPathways
WP15Selenium Pathway
Pathway Interaction Database
hnf3bpathwayFOXA2 and FOXA3 transcription factor networks
Reactome
REACT_19118SLC-mediated transmembrane transport
REACT_798Platelet activation, signaling and aggregation
REACT_604Hemostasis
REACT_318Platelet degranulation
REACT_11040Bile acid and bile salt metabolism
REACT_13621HDL-mediated lipid transport
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_602Lipid digestion, mobilization, and transport
REACT_11042Recycling of bile acids and salts
REACT_6823Lipoprotein metabolism
REACT_15518Transmembrane transport of small molecules
REACT_22258Metabolism of lipids and lipoproteins
REACT_22285Transport of vitamins, nucleosides, and related molecules
REACT_23988Transport of organic anions
REACT_111217Metabolism
REACT_160300Binding and Uptake of Ligands by Scavenger Receptors
REACT_160163Scavenging of heme from plasma
Homo sapiens (human)ALBNP_000468.1
Pan troglodytes (chimpanzee)ALBXP_517233.3
Macaca mulatta (Rhesus monkey)ALBXP_001103956.1
Canis lupus familiaris (dog)ALBNP_001003026.1
Bos taurus (cattle)ALBNP_851335.1
Mus musculus (house mouse)AlbNP_033784.2
Rattus norvegicus (Norway rat)AlbNP_599153.2
Gallus gallus (chicken)ALBNP_990592.1
Xenopus (Silurana) tropicalis (western clawed frog)cars2NP_001004887.2
Process
IDNameEvidence
GO:0001895retina homeostasisIEP
GO:0002576platelet degranulationTAS
GO:0006810transportTAS
GO:0007584response to nutrientIEA
GO:0007596blood coagulationTAS
GO:0008206bile acid metabolic processTAS
GO:0009267cellular response to starvationIDA
GO:0010033response to organic substanceIEA
GO:0015721bile acid and bile salt transportTAS
GO:0019836hemolysis by symbiont of host erythrocytesIDA
GO:0030168platelet activationTAS
GO:0042157lipoprotein metabolic processTAS
GO:0043066negative regulation of apoptotic processIDA
GO:0043069negative regulation of programmed cell deathNAS
GO:0043252sodium-independent organic anion transportTAS
GO:0044281small molecule metabolic processTAS
GO:0046010positive regulation of circadian sleep/wake cycle, non-REM sleepIEA
GO:0046689response to mercury ionIEA
GO:0051659maintenance of mitochondrion locationIDA
GO:0055085transmembrane transportTAS
GO:0070541response to platinum ionIEA
Component
IDNameEvidence
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005604basement membraneIEA
GO:0005615extracellular spaceIDA
GO:0005634nucleusIDA
GO:0031093platelet alpha granule lumenTAS
GO:0043234protein complexIDA
GO:0070062extracellular vesicular exosomeIDA
GO:0072562blood microparticleIDA
Function
IDNameEvidence
GO:0003677DNA bindingIDA
GO:0005504fatty acid bindingIDA
GO:0005504fatty acid bindingNAS
GO:0005507copper ion bindingNAS
GO:0005515protein bindingIPI
GO:0008144drug bindingIDA
GO:0008144drug bindingNAS
GO:0008270zinc ion bindingIEA
GO:0015643toxic substance bindingIDA
GO:0016209antioxidant activityNAS
GO:0019825oxygen bindingIDA
GO:0019899enzyme bindingIEA
GO:0030170pyridoxal phosphate bindingIDA
GO:0051087chaperone bindingIPI
GeneCards ALB
UniProt P02768
Vega OTTHUMG00000129919
MIM 103600
Ensembl ENSG00000163631
HGNC 399
HPRD 00062

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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