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Sequence in raw or FASTA format:

Database:

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EWSR1 EWS RNA-binding protein 1 [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu26616 NM_001163286 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu26751 NM_001163287 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 5, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu27045 NM_005243 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu27117 NM_013986 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu27250 NM_001163285 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu53446 XM_005261389 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X1, mRNA. pcDNA3.1+-DYK On-demand 12-14 $279.00
OHu53447 XM_006724166 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu53448 XM_006724167 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu53449 XM_005261390 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X2, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu26616C NM_001163286 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 4, mRNA. Customized vector On-demand 7-9 $269.00
OHu26751C NM_001163287 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 5, mRNA. Customized vector In-stock 5-7 $149.00
OHu27045C NM_005243 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu27117C NM_013986 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu27250C NM_001163285 Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu53446C XM_005261389 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X1, mRNA. Customized vector On-demand 12-14 $329.00
OHu53447C XM_006724166 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X3, mRNA. Customized vector On-demand 7-9 $269.00
OHu53448C XM_006724167 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X4, mRNA. Customized vector On-demand 7-9 $269.00
OHu53449C XM_005261390 PREDICTED: Homo sapiens EWS RNA-binding protein 1 (EWSR1), transcript variant X2, mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol EWSR1
Entrez Gene ID 2130
Full Name EWS RNA-binding protein 1
Synonyms EWS, bK984G1.4
General protein information
Preferred Names
RNA-binding protein EWS
Names
RNA-binding protein EWS
Ewing sarcoma breakpoint region 1
Ewings sarcoma EWS-Fli1 (type 1) oncogene
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

22

22q12.2

Summary This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009].
Disorder

MIM: 133450

Ewing sarcoma, 612219 (3); Neuroepithelioma, 612219 (3)

mRNA Protein Product Sequence Price Select
NM_001163285, 253970501 NP_001156757, 253970502 RNA-binding protein EWS isoform 3 ORF Sequence $700.00
NM_001163286, 253970503 NP_001156758, 253970504 RNA-binding protein EWS isoform 4 ORF Sequence $700.00
NM_001163287, 253970505 NP_001156759, 253970506 RNA-binding protein EWS isoform 5 ORF Sequence $269.00
NM_005243, 253970497 NP_005234, 4885225 RNA-binding protein EWS isoform 2 ORF Sequence $490.00
NM_013986, 253970499 NP_053733, 253970500 RNA-binding protein EWS isoform 1 ORF Sequence $700.00
XM_005261389, 530419639 XP_005261446, 530419640 RNA-binding protein EWS isoform X1 ORF Sequence $700.00
XM_005261390, 578837008 XP_005261447, 530419642 RNA-binding protein EWS isoform X2 ORF Sequence $700.00
XM_006724166, 578837004 XP_006724229, 578837005 RNA-binding protein EWS isoform X3 ORF Sequence $700.00
XM_006724167, 578837006 XP_006724230, 578837007 RNA-binding protein EWS isoform X4 ORF Sequence $700.00
KEGG
hsa05202Transcriptional misregulation in cancer
Pathway Interaction Database
bard1pathwayBARD1 signaling events
Homo sapiens (human)EWSR1NP_053733.2
Danio rerio (zebrafish)ewsr1aNP_001108610.1
Process
IDNameEvidence
GO:0006351transcription, DNA-templatedIEA
GO:0006355regulation of transcription, DNA-templatedIEA
Component
IDNameEvidence
GO:0005634nucleusIEA
GO:0005737cytoplasmIEA
GO:0005886plasma membraneIEA
Function
IDNameEvidence
GO:0000166nucleotide bindingIEA
GO:0003723RNA bindingTAS
GO:0005515protein bindingIPI
GO:0005516calmodulin bindingIEA
GO:0008270zinc ion bindingIEA
GO:0042802identical protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards EWSR1
UniProt Q01844
Vega OTTHUMG00000151107
MIM 133450
Ensembl ENSG00000182944
HGNC 3508
HPRD 00592

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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