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Sequence in raw or FASTA format:

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FANCA Fanconi anemia, complementation group A [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_000135 Homo sapiens Fanconi anemia, complementation group A (FANCA), transcript variant 1, mRNA. ORF Sequence $1528.80
Peptide Services
Antibody Services
Protein Services
NM_001018112 Homo sapiens Fanconi anemia, complementation group A (FANCA), transcript variant 2, mRNA. ORF Sequence $259.26
Peptide Services
Antibody Services
Protein Services


Gene Symbol FANCA
Entrez Gene ID 2175
Full Name Fanconi anemia, complementation group A
Synonyms FA, FA-H, FA1, FAA, FACA, FAH, FANCH, MGC75158
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16q24.3

Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008].
Disorder

MIM: 607139

Fanconi anemia, complementation group A, 227650 (3)

mRNA Protein Product Sequence Price Select
NM_000135, 66880552 NP_000126, 66880553 Fanconi anemia group A protein isoform a Full Length $2457.00
ORF Sequence $1528.80
NM_001018112, 66879665 NP_001018122, 66879666 Fanconi anemia group A protein isoform b Full Length $485.17
ORF Sequence $259.26
KEGG
hsa03460Fanconi anemia pathway
hsa_M00413FA core complex
Pathway Interaction Database
bard1pathwayBARD1 signaling events
Reactome
REACT_18410Fanconi Anemia pathway
REACT_216DNA Repair
Homo sapiens (human)FANCANP_000126.2
Pan troglodytes (chimpanzee)FANCAXP_003315314.2
Canis lupus familiaris (dog)FANCAXP_850915.2
Bos taurus (cattle)FANCANP_001193532.1
Mus musculus (house mouse)FancaNP_058621.2
Rattus norvegicus (Norway rat)FancaNP_001101925.1
Gallus gallus (chicken)FANCANP_001127831.1
Danio rerio (zebrafish)fancaNP_001035725.1
GeneCards FANCA
UniProt Q86U55, O15360
MIM 607139
Ensembl ENSG00000187741
HGNC 3582
HPRD 06186

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
Fanconi anemia group A protein
Names
Fanconi anemia group A protein
Fanconi anemia, type 1
Fanconi anemia, complementation group H

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