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FANCG Fanconi anemia, complementation group G [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu25922 NM_004629 Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu25922C NM_004629 Homo sapiens Fanconi anemia, complementation group G (FANCG), mRNA. Customized vector On-demand 7-9 $269.00

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Gene Symbol FANCG
Entrez Gene ID 2189
Full Name Fanconi anemia, complementation group G
Synonyms FAG, XRCC9
General protein information
Preferred Names
Fanconi anemia group G protein
Names
Fanconi anemia group G protein
DNA repair protein XRCC9
X-ray repair, complementing defective, in Chinese hamster, 9
X-ray repair complementing defective repair in Chinese hamster cells 9
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

9

9p13

Summary The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G. [provided by RefSeq, Jul 2008].
Disorder

MIM: 602956

Fanconi anemia, complementation group G (3)

mRNA Protein Product Sequence Price Select
NM_004629, 4759335 NP_004620, 4759336 Fanconi anemia group G protein ORF Sequence $700.00
KEGG
hsa03460Fanconi anemia pathway
hsa_M00413FA core complex
WikiPathways
WP2446RB in Cancer
Pathway Interaction Database
bard1pathwayBARD1 signaling events
Reactome
REACT_216DNA Repair
REACT_18410Fanconi Anemia pathway
REACT_120956Cellular responses to stress
REACT_200744HSF1 activation
REACT_200819Cellular response to heat stress
Homo sapiens (human)FANCGNP_004620.1
Pan troglodytes (chimpanzee)FANCGXP_001165190.1
Macaca mulatta (Rhesus monkey)FANCGXP_001092322.1
Canis lupus familiaris (dog)FANCGXP_854703.1
Bos taurus (cattle)FANCGNP_001095757.1
Mus musculus (house mouse)FancgNP_444311.1
Rattus norvegicus (Norway rat)FancgXP_006238187.1
Gallus gallus (chicken)FANCGNP_989709.1
Danio rerio (zebrafish)fancgNP_991202.1
Xenopus (Silurana) tropicalis (western clawed frog)fancgNP_001120193.1
Process
IDNameEvidence
GO:0000075cell cycle checkpointTAS
GO:0001541ovarian follicle developmentIEA
GO:0006281DNA repairTAS
GO:0007005mitochondrion organizationIMP
GO:0007286spermatid developmentIEA
GO:0009314response to radiationIEA
Component
IDNameEvidence
GO:0005654nucleoplasmTAS
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005739mitochondrionIDA
GO:0005886plasma membraneIDA
GO:0043240Fanconi anaemia nuclear complexIDA
Function
IDNameEvidence
GO:0003684damaged DNA bindingTAS
GO:0005515protein bindingIPI
GeneCards FANCG
UniProt Q53XM5, O15287
Vega OTTHUMG00000019850
MIM 602956
Ensembl ENSG00000221829
HGNC 3588
HPRD 04262

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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