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FGF8 fibroblast growth factor 8 (androgen-induced) [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_001206389 Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant G, mRNA. GenEZ ORF Cloning In-stock $248.00 $199.00 10
NM_006119 Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant B, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_033163 Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant F, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10
NM_033164 Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant E, mRNA. GenEZ ORF Cloning On-demand $399.00 14
NM_033165 Homo sapiens fibroblast growth factor 8 (androgen-induced) (FGF8), transcript variant A, mRNA. GenEZ ORF Cloning In-stock $308.00 $259.00 10

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Related Services

Gene Symbol FGF8
Entrez Gene ID 2253
Full Name fibroblast growth factor 8 (androgen-induced)
Synonyms AIGF, FGF-8, HBGF-8, KAL6, MGC149376
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q24

Summary The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants. [provided by RefSeq, Jul 2008].
Disorder

MIM: 600483

Kallmann syndrome 6, 612702 (3)

mRNA Protein Product Sequence Price Select
NM_001206389, 329755302 NP_001193318, 329755303 fibroblast growth factor 8 isoform G ORF Sequence $99.00
NM_006119, 298919217 NP_006110, 5174439 fibroblast growth factor 8 isoform B precursor ORF Sequence $159.00
NM_033163, 298919216 NP_149353, 15147346 fibroblast growth factor 8 isoform F precursor ORF Sequence $159.00
NM_033164, 298919214 NP_149354, 15147348 fibroblast growth factor 8 isoform E precursor ORF Sequence $250.00
NM_033165, 298919215 NP_149355, 15147350 fibroblast growth factor 8 isoform A precursor ORF Sequence $159.00
KEGG
hsa05218Melanoma
hsa04151PI3K-Akt signaling pathway
hsa04810Regulation of actin cytoskeleton
hsa04010MAPK signaling pathway
hsa05200Pathways in cancer
WikiPathways
WP1591Heart Development
WP51Regulation of Actin Cytoskeleton
WP2064Neural Crest Differentiation
Reactome
REACT_75829PIP3 activates AKT signaling
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_115596Signaling by ERBB4
REACT_976PI3K Cascade
REACT_11061Signalling by NGF
REACT_147694DAP12 interactions
REACT_115755Signaling by ERBB2
REACT_9508FGFR3b ligand binding and activation
REACT_121153Signaling by activated point mutants of FGFR1
REACT_118773Signaling by the B Cell Receptor (BCR)
REACT_111184Negative regulation of FGFR signaling
REACT_115961PI3K events in ERBB4 signaling
REACT_21310Phospholipase C-mediated cascade
REACT_147814DAP12 signaling
REACT_6802Innate Immune System
REACT_116008PI3K events in ERBB2 signaling
REACT_111040Signaling by SCF-KIT
REACT_9510FGFR3c ligand binding and activation
REACT_9396FGFR ligand binding and activation
REACT_1195Insulin receptor signalling cascade
REACT_9452FGFR4 ligand binding and activation
REACT_21374SHC-mediated cascade
REACT_120863Activated point mutants of FGFR2
REACT_6900Immune System
REACT_118638Downstream Signaling Events Of B Cell Receptor (BCR)
REACT_9470Signaling by FGFR
REACT_12578GAB1 signalosome
REACT_21272Downstream signaling of activated FGFR
REACT_9483FGFR1 ligand binding and activation
REACT_147723PI3K/AKT Signaling in Cancer
REACT_21270PI-3K cascade
REACT_498Signaling by Insulin receptor
REACT_9439FGFR3 ligand binding and activation
REACT_75774Adaptive Immune System
REACT_16888Signaling by PDGF
REACT_17025Downstream signal transduction
REACT_111102Signal Transduction
REACT_121155Signaling by FGFR2 mutants
REACT_121249Signaling by FGFR3 mutants
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_120736Signaling by FGFR in disease
REACT_116125Disease
REACT_120999Signaling by FGFR1 mutants
REACT_9390FGFR2 ligand binding and activation
REACT_121398Signaling by FGFR mutants
REACT_121337Signaling by activated point mutants of FGFR3
REACT_9413FGFR2c ligand binding and activation
REACT_12464PI3K/AKT activation
REACT_147727Constitutive PI3K/AKT Signaling in Cancer
REACT_762IRS-related events
REACT_21247FRS2-mediated cascade
REACT_332IRS-mediated signalling
REACT_9515FGFR1c ligand binding and activation
Homo sapiens (human)FGF8NP_149353.1
Canis lupus familiaris (dog)FGF8XP_851783.3
Bos taurus (cattle)FGF8NP_001193607.1
Mus musculus (house mouse)Fgf8NP_001159833.1
Rattus norvegicus (Norway rat)Fgf8NP_579820.1
Gallus gallus (chicken)FGF8NP_001012785.1
Danio rerio (zebrafish)fgf8aNP_571356.2
GeneCards FGF8
PDB 2FDB
UniProt P55075, A1A515
MIM 600483
Ensembl ENSG00000107831
HGNC 3686
HPRD 02727

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
fibroblast growth factor 8
Names
fibroblast growth factor 8
androgen-induced growth factor
heparin-binding growth factor 8

Interactant



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