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FOXG1 forkhead box G1 [Homo sapiens (human)]


RefSeq Accession Definition Sequence Price Select
NM_005249 Homo sapiens forkhead box G1 (FOXG1), mRNA. Full Length $754.00
ORF Sequence $426.30


Gene Symbol FOXG1
Entrez Gene ID 2290
Full Name forkhead box G1
Synonyms BF1, BF2, FHKL3, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, FOXG1A, FOXG1B, FOXG1C, HBF-1, HBF-2, HBF-3, HBF-G2, HBF2, HFK1, HFK2, HFK3, KHL2, QIN
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

14

14q13
Summary This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon. [provided by RefSeq].
Disorder

MIM: 164874

Rett syndrome, congenital variant, 613454 (3)
mRNA NM_005249, 32307176
Protein NP_005240, 32307177
Product forkhead box protein G1
RefSeq Status REVIEWED
Pathway Interaction Database
smad2_3nuclearpathwayRegulation of nuclear SMAD2/3 signaling
WikiPathways
WP366TGF-beta Receptor Signaling Pathway
Homo sapiens (human)FOXG1NP_005240.3
Canis lupus familiaris (dog)FOXG1XP_547758.2
Bos taurus (cattle)FOXG1XP_001249413.1
Mus musculus (house mouse)Foxg1NP_032267.1
Rattus norvegicus (Norway rat)Foxg1NP_036692.1
Gallus gallus (chicken)FOXG1NP_990524.1
Danio rerio (zebrafish)foxg1aNP_571142.1
Process
IDNameEvidence
GO:0002052positive regulation of neuroblast proliferationISS
GO:0006355regulation of transcription, DNA-dependentNAS
GO:0007275multicellular organismal developmentIEA
GO:0007346regulation of mitotic cell cycleISS
GO:0007420brain developmentTAS
GO:0009792embryo development ending in birth or egg hatchingISS
GO:0009888tissue developmentISS
GO:0009953dorsal/ventral pattern formationISS
GO:0016199axon midline choice point recognitionISS
GO:0021954central nervous system neuron developmentISS
GO:0030902hindbrain developmentISS
GO:0035058sensory cilium assemblyISS
GO:0042472inner ear morphogenesisISS
GO:0043584nose developmentISS
GO:0045665negative regulation of neuron differentiationISS
GO:0045787positive regulation of cell cycleISS
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterISS
GO:0051090regulation of sequence-specific DNA binding transcription factor activityISS
Component
IDNameEvidence
GO:0005634nucleusNAS
GO:0005667transcription factor complexISS
Function
IDNameEvidence
GO:0003677DNA bindingTAS
GO:0003690double-stranded DNA bindingISS
GO:0003705sequence-specific enhancer binding RNA polymerase II transcription factor activityISS
GO:0005515protein bindingIPI
GO:0008134transcription factor bindingISS
GO:0008301DNA bending activityISS
GO:0043565sequence-specific DNA bindingIEA
GeneCards FOXG1
UniProt P55316
MIM 164874
Ensembl ENSG00000176165
HGNC 3811
HPRD 01283

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