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FLI1 Fli-1 proto-oncogene, ETS transcription factor [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu20383 NM_002017 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 1, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu20623 NM_001271010 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu20678 NM_001167681 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 2, mRNA. pcDNA3.1+-DYK In-stock 5-7 $99.00
OHu21072 NM_001271012 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu20383C NM_002017 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 1, mRNA. Customized vector In-stock 5-7 $149.00
OHu20623C NM_001271010 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu20678C NM_001167681 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 2, mRNA. Customized vector In-stock 5-7 $149.00
OHu21072C NM_001271012 Homo sapiens Fli-1 proto-oncogene, ETS transcription factor (FLI1), transcript variant 4, mRNA. Customized vector On-demand 7-9 $209.00

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Gene Symbol FLI1
Entrez Gene ID 2313
Full Name Fli-1 proto-oncogene, ETS transcription factor
Synonyms EWSR2, SIC-1
General protein information
Preferred Names
Friend leukemia integration 1 transcription factor
Names
Friend leukemia integration 1 transcription factor
proto-oncogene Fli-1
transcription factor ERGB
Ewing sarcoma breakpoint region 2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

11

11q24.1-q24.3

Summary This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Disorder

MIM: 193067

mRNA Protein Product Sequence Price Select
NM_001167681, 328550502 NP_001161153, 264681554 Friend leukemia integration 1 transcription factor isoform 2 ORF Sequence $360.00
NM_001271010, 401871075 NP_001257939, 401871076 Friend leukemia integration 1 transcription factor isoform 3 ORF Sequence $400.00
NM_001271012, 401871077 NP_001257941, 401871078 Friend leukemia integration 1 transcription factor isoform 4 ORF Sequence $300.00
NM_002017, 401871074 NP_002008, 7110593 Friend leukemia integration 1 transcription factor isoform 1 ORF Sequence $360.00
KEGG
hsa05202Transcriptional misregulation in cancer
Homo sapiens (human)FLI1NP_002008.2
Pan troglodytes (chimpanzee)FLI1XP_508856.3
Macaca mulatta (Rhesus monkey)FLI1XP_002799924.1
Canis lupus familiaris (dog)FLI1XP_546404.2
Bos taurus (cattle)FLI1NP_001039763.1
Mus musculus (house mouse)Fli1NP_032052.1
Rattus norvegicus (Norway rat)Fli1NP_001017381.1
Gallus gallus (chicken)FLI1NP_001026079.1
Danio rerio (zebrafish)fli1aNP_571423.1
Xenopus (Silurana) tropicalis (western clawed frog)fli1NP_001096189.1
Process
IDNameEvidence
GO:0006357regulation of transcription from RNA polymerase II promoterIBA
GO:0006366transcription from RNA polymerase II promoterIBA
GO:0007599hemostasisTAS
GO:0009887organ morphogenesisTAS
GO:0030154cell differentiationIBA
Component
IDNameEvidence
GO:0005634nucleusIBA
Function
IDNameEvidence
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activityIBA
GO:0003677DNA bindingTAS
GO:0003700sequence-specific DNA binding transcription factor activityTAS
GO:0043565sequence-specific DNA bindingIEA
GeneCards FLI1
UniProt Q01543
Vega OTTHUMG00000165792
MIM 193067
Ensembl ENSG00000151702
HGNC 3749
HPRD 01901

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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