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Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


FLNC filamin C, gamma [Homo sapiens (human)]


RefSeq Accession Definition Services Price Order
NM_001127487 Homo sapiens filamin C, gamma (FLNC), transcript variant 2, mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services
NM_001458 Homo sapiens filamin C, gamma (FLNC), transcript variant 1, mRNA. ORF Sequence Quote
Peptide Services
Antibody Services
Protein Services


Gene Symbol FLNC
Entrez Gene ID 2318
Full Name filamin C, gamma
Synonyms ABP-280, ABP280A, ABPA, ABPL, FLJ10186, FLN2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

7

7q32-q35

Summary This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder

MIM: 102565

Myopathy, myofibrillar, filamin C-related, 609524 (3)

mRNA Protein Product Sequence Price Select
NM_001127487, 188595686 NP_001120959, 188595687 filamin-C isoform b Full Length $0.00
ORF Sequence $0.00
NM_001458, 188595685 NP_001449, 116805322 filamin-C isoform a Full Length $0.00
ORF Sequence $0.00
KEGG
hsa04510Focal adhesion
hsa04010MAPK signaling pathway
hsa05132Salmonella infection
Reactome
REACT_111155Cell-Cell communication
REACT_20676Cell junction organization
REACT_20649Cell-extracellular matrix interactions
Homo sapiens (human)FLNCNP_001449.3
Pan troglodytes (chimpanzee)FLNCXP_519364.3
Macaca mulatta (Rhesus monkey)LOC700223XP_002808411.1
Canis lupus familiaris (dog)FLNCXP_539385.1
Bos taurus (cattle)FLNCNP_001193919.1
Mus musculus (house mouse)FlncNP_001074654.1
Rattus norvegicus (Norway rat)FlncXP_342654.2
Gallus gallus (chicken)FLNCNP_989904.1
Danio rerio (zebrafish)flncaXP_002666982.1
Caenorhabditis elegansY66H1B.3NP_499912.1
GeneCards FLNC
PDB 2D7M, 2D7P, 2D7O, 2K9U, 2D7N, 2NQC, 1V05, 2D7Q
UniProt Q59H94, Q14315
MIM 102565
Ensembl ENSG00000128591
HGNC 3756
HPRD 00018

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
filamin-C
Names
filamin-C
FLN-C
filamin 2
filamin-2
ABP-280-like protein
ABP-L, gamma filamin
actin binding protein 280
actin-binding-like protein

Interactant

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