USP24 ubiquitin specific peptidase 24 [Homo sapiens (human)]
| Gene Symbol | USP24 |
| Entrez Gene ID | 23358 |
| Full Name | ubiquitin specific peptidase 24 |
| Synonyms | FLJ31309, KIAA1057 |
| Gene Type | protein-coding |
| Organism | Homo sapiens (human) |
| Genome |
1 1p32.3 |
| Summary | Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM]. |
| Disorder | MIM: 610569 |
| mRNA | NM_015306, 260064008 |
| Protein | NP_056121, 260064009 |
| Product | ubiquitin carboxyl-terminal hydrolase 24 |
| RefSeq Status | VALIDATED |
| Homo sapiens (human) | USP24 | NP_056121.2 |
| Pan troglodytes (chimpanzee) | USP24 | XP_513431.2 |
| Canis lupus familiaris (dog) | USP24 | XP_536697.2 |
| Rattus norvegicus (Norway rat) | Usp24 | XP_233260.4 |
| Gallus gallus (chicken) | USP24 | XP_422499.2 |
| Danio rerio (zebrafish) | usp24 | XP_002665714.1 |
| Caenorhabditis elegans | T24B8.7 | NP_495931.2 |
| ID | Name | Evidence |
| GO:0006511 | ubiquitin-dependent protein catabolic process | IEA |
Function
| ID | Name | Evidence |
| GO:0004221 | ubiquitin thiolesterase activity | IEA |
| GO:0005488 | binding | IEA |
| GO:0008233 | peptidase activity | IEA |
| GO:0008234 | cysteine-type peptidase activity | IEA |
| GeneCards | USP24 |
| UniProt | Q9UPU5 |
| MIM | 610569 |
| Ensembl | ENSG00000162402 |
| HGNC | 12623 |
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