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TARDBP TAR DNA binding protein [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_007375 Homo sapiens TAR DNA binding protein (TARDBP), mRNA. GenEZ ORF Cloning In-stock $418.00 $369.00 10

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Gene Symbol TARDBP
Entrez Gene ID 23435
Full Name TAR DNA binding protein
Synonyms ALS10, TDP-43
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p36.22

Summary HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008].
Disorder

MIM: 605078

Amyotrophic lateral sclerosis 10, with or without FTD, 612069 (3);

mRNA Protein Product Sequence Price Select
NM_007375, 42741653 NP_031401, 6678271 TAR DNA-binding protein 43 ORF Sequence $269.00
Homo sapiens (human)TARDBPNP_031401.1
Pan troglodytes (chimpanzee)TARDBPXP_514380.2
Macaca mulatta (Rhesus monkey)TARDBPXP_001102660.1
Canis lupus familiaris (dog)TARDBPXP_535409.3
Bos taurus (cattle)TARDBPNP_001039950.2
Mus musculus (house mouse)TardbpNP_663531.1
Gallus gallus (chicken)TARDBPNP_001026049.1
Danio rerio (zebrafish)tardbpNP_958884.1
Drosophila melanogaster (fruit fly)TBPHNP_726373.1
Caenorhabditis eleganstdp-1NP_001022166.1
GeneCards TARDBP
PDB 1WF0, 2CQG
UniProt Q9H256, Q13148
MIM 605078
Ensembl ENSG00000120948
HGNC 11571
HPRD 05466

GeneRIFs: Gene References Into Functions What's a GeneRIF?

General protein information

Preferred Names
TAR DNA-binding protein 43
Names
TAR DNA-binding protein 43
TAR DNA-binding protein-43

Interactant



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