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Sequence in raw or FASTA format:

Database:

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FUS FUS RNA binding protein [Homo sapiens (human)]


Clone ID RefSeq Accession Definition Vector Stock Status *Turnaround time Price Order
OHu24541 NM_001170937 Homo sapiens FUS RNA binding protein (FUS), transcript variant 4, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu24554 NM_001170634 Homo sapiens FUS RNA binding protein (FUS), transcript variant 3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu24555 NM_004960 Homo sapiens FUS RNA binding protein (FUS), transcript variant 1, mRNA. pcDNA3.1+-DYK On-demand 7-9 $219.00
OHu49109 XM_005255233 PREDICTED: Homo sapiens fused in sarcoma (FUS), transcript variant X3, mRNA. pcDNA3.1+-DYK On-demand 7-9 $159.00
OHu24541C NM_001170937 Homo sapiens FUS RNA binding protein (FUS), transcript variant 4, mRNA. Customized vector On-demand 7-9 $269.00
OHu24554C NM_001170634 Homo sapiens FUS RNA binding protein (FUS), transcript variant 3, mRNA. Customized vector On-demand 7-9 $269.00
OHu24555C NM_004960 Homo sapiens FUS RNA binding protein (FUS), transcript variant 1, mRNA. Customized vector On-demand 7-9 $269.00
OHu49109C XM_005255233 PREDICTED: Homo sapiens fused in sarcoma (FUS), transcript variant X3, mRNA. Customized vector On-demand 7-9 $209.00

*Business Day

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Gene Symbol FUS
Entrez Gene ID 2521
Full Name FUS RNA binding protein
Synonyms ALS6, ETM4, FUS1, HNRNPP2, POMP75, TLS
General protein information
Preferred Names
RNA-binding protein FUS
Names
RNA-binding protein FUS
oncogene FUS
oncogene TLS
fus-like protein
75 kDa DNA-pairing protein
fusion gene in myxoid liposarcoma
translocated in liposarcoma protein
heterogeneous nuclear ribonucleoprotein P2
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

16

16p11.2

Summary This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq, Sep 2009].
Disorder

MIM: 137070

Amyotrophic lateral sclerosis 6, autosomal recessive, with or without

mRNA Protein Product Sequence Price Select
NM_001170634, 283135200 NP_001164105, 283135201 RNA-binding protein FUS isoform 2 ORF Sequence $550.00
NM_001170937, 283135172 NP_001164408, 283135173 RNA-binding protein FUS isoform 3 ORF Sequence $550.00
NM_004960, 270265814 NP_004951, 4826734 RNA-binding protein FUS isoform 1 ORF Sequence $550.00
XM_005255233, 578828504 XP_005255290, 530407875 RNA-binding protein FUS isoform X3 ORF Sequence $400.00
KEGG
hsa05202Transcriptional misregulation in cancer
WikiPathways
WP411mRNA processing
Reactome
REACT_71Gene Expression
REACT_1735mRNA Splicing
REACT_467mRNA Splicing - Major Pathway
REACT_125Processing of Capped Intron-Containing Pre-mRNA
Process
IDNameEvidence
GO:0000398mRNA splicing, via spliceosomeTAS
GO:0008219cell deathIEA
GO:0008380RNA splicingTAS
GO:0010467gene expressionTAS
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005654nucleoplasmTAS
GO:0005730nucleolusIDA
GO:0005737cytoplasmIEA
Function
IDNameEvidence
GO:0000166nucleotide bindingIEA
GO:0003677DNA bindingIEA
GO:0003723RNA bindingTAS
GO:0005515protein bindingIPI
GO:0008270zinc ion bindingIEA
GO:0042802identical protein bindingIPI
GO:0044822poly(A) RNA bindingIDA
GeneCards FUS
UniProt Q6IBQ5, P35637, Q13344
Vega OTTHUMG00000132395
MIM 137070
Ensembl ENSG00000089280
HGNC 4010
HPRD 00660

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interactant

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