• THAT   AND
  • THAT   AND


Sequence in raw or FASTA format:

Database:

Blast Method:

 
 


MFSD8 major facilitator superfamily domain containing 8 [Homo sapiens (human)]


RefSeq Accession Definition Service Stock Status Price *Turnaround time Order
NM_152778 Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), mRNA. GenEZ ORF Cloning In-stock $509.00 $460.00 12
XM_005262893 PREDICTED: Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), transcript variant X1, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_005262896 PREDICTED: Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), transcript variant X4, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_005262897 PREDICTED: Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), transcript variant X5, mRNA. GenEZ ORF Cloning On-demand $699.00 18
XM_005262898 PREDICTED: Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), transcript variant X6, mRNA. GenEZ ORF Cloning On-demand $549.00 14
XM_005262900 PREDICTED: Homo sapiens major facilitator superfamily domain containing 8 (MFSD8), transcript variant X8, mRNA. GenEZ ORF Cloning On-demand $399.00 14

*Business Day

Related Services

Gene Symbol MFSD8
Entrez Gene ID 256471
Full Name major facilitator superfamily domain containing 8
Synonyms CLN7
General protein information
Preferred Names
major facilitator superfamily domain-containing protein 8
Names
major facilitator superfamily domain-containing protein 8
ceroid-lipofuscinosis neuronal protein 7
ceroid-lipofuscinosis, neuronal 7, late infantile
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

4

4q28.2

Summary This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq, Oct 2008].
Disorder

MIM: 611124

Ceroid lipofuscinosis, neuronal, 7, 610951 (3)

mRNA Protein Product Sequence Price Select
NM_152778, 199560897 NP_689991, 22749525 major facilitator superfamily domain-containing protein 8 ORF Sequence $360.00
XM_005262893, 530377480 XP_005262950, 530377481 major facilitator superfamily domain-containing protein 8 isoform X1 ORF Sequence $550.00
XM_005262896, 530377486 XP_005262953, 530377487 major facilitator superfamily domain-containing protein 8 isoform X4 ORF Sequence $550.00
XM_005262897, 530377488 XP_005262954, 530377489 major facilitator superfamily domain-containing protein 8 isoform X5 ORF Sequence $550.00
XM_005262898, 578809002 XP_005262955, 530377491 major facilitator superfamily domain-containing protein 8 isoform X6 ORF Sequence $400.00
XM_005262900, 530377494 XP_005262957, 530377495 major facilitator superfamily domain-containing protein 8 isoform X8 ORF Sequence $250.00
KEGG
hsa04142Lysosome
Homo sapiens (human)MFSD8NP_689991.1
Pan troglodytes (chimpanzee)MFSD8XP_526685.2
Macaca mulatta (Rhesus monkey)LOC713336XP_002804236.1
Canis lupus familiaris (dog)MFSD8XP_533294.3
Bos taurus (cattle)MFSD8NP_001192752.1
Mus musculus (house mouse)Mfsd8NP_082416.2
Gallus gallus (chicken)MFSD8XP_004941064.1
Danio rerio (zebrafish)mfsd8NP_001038513.1
Drosophila melanogaster (fruit fly)CG8596NP_648107.3
Caenorhabditis elegansY53G8AR.7NP_001022903.1
Caenorhabditis elegansCELE_W01B6.3NP_501823.2
Caenorhabditis elegansCELE_ZK550.2NP_503058.1
Caenorhabditis elegansT28C12.2NP_504616.1
Caenorhabditis elegansCELE_F14D7.6NP_001256575.1
Caenorhabditis elegansT28C12.1NP_504617.2
Caenorhabditis elegansW05E10.1NP_505957.1
Caenorhabditis elegansF27D9.2NP_509296.1
Caenorhabditis elegansF57A8.7NP_505586.1
Caenorhabditis elegansF58G11.4NP_001256536.1
Caenorhabditis elegansF52F10.2NP_503443.1
Caenorhabditis elegansW03C9.6NP_496546.2
Caenorhabditis eleganssrsx-34NP_505340.1
Caenorhabditis elegansC25E10.5NP_505338.1
Caenorhabditis elegansC25E10.4NP_505339.2
Xenopus (Silurana) tropicalis (western clawed frog)mfsd8XP_002932088.1
Process
IDNameEvidence
GO:0008219cell deathIEA
GO:0055085transmembrane transportIEA
Component
IDNameEvidence
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005765lysosomal membraneIDA
GO:0016021integral component of membraneIEA
GO:0043231intracellular membrane-bounded organelleIDA
GeneCards MFSD8
UniProt Q8NHS3
Vega OTTHUMG00000133303
MIM 611124
Ensembl ENSG00000164073
HGNC 28486
HPRD 14557

GeneRIFs: Gene References Into Functions What's a GeneRIF?

What is the normal function of the MFSD8 gene?

The MFSD8 gene provides instructions for making a protein whose function is unknown. The MFSD8 protein is found in cell compartments called lysosomes, which digest and recycle different types of molecules. The MFSD8 protein belongs to a large group of related proteins called the major facilitator superfamily of secondary active transporter proteins. Proteins in this family move certain molecules between structures in cells or in and out of cells. While it is likely that the MFSD8 protein transports molecules, the specific molecules it moves are unknown. The MFSD8 protein probably transports substances across the membranes of lysosomes.

Interactant

Our customer service representatives are available 24 hours a day, Monday through Friday; please contact us anytime for assistance.